{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T19:21:56Z","timestamp":1774639316444,"version":"3.50.1"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T00:00:00Z","timestamp":1644364800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951122000300_as1\"><jats:title>Objectives:<\/jats:title><jats:p>To characterise the use of peripherally inserted central catheters in paediatric cardiac patients and to identify risk factors associated with their complications.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122000300_as2\"><jats:title>Materials and Methods:<\/jats:title><jats:p>Observational retrospective cohort study in paediatric cardiac patients who underwent peripherally inserted central catheter placement in a tertiary children\u2019s hospital from January 2000 to June 2018.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122000300_as3\"><jats:title>Results:<\/jats:title><jats:p>1822 cardiac patients underwent 2952 peripherally inserted central catheter placements in the study period. Median age was 29 days, with survival to hospital discharge of 96.4%. Successful placement achieved 94.5% of attempts, with a median line duration of 12 days. Factors associated with successful placement were the use of general anaesthesia (odds ratio 7.52, p &lt; 0.001) and year of placement (odds ratio 1.08, p &lt; 0.001). The incidence of complications was 28.6%, with thrombosis\/occlusion being the most frequent (33%). Thrombosis\/occlusion were associated with two and three lumens (odds ratio 1.96, p &lt; 0.001 and 4.63, p = 0.037, respectively). Lines placed by interventional radiology had decreased infiltration (odds ratio 0.20, p = 0.002) and lower migration\/malposition (odds ratio 0.36, p &lt; 0.001). The use of maintenance intravenous fluids (odds ratio 3.98, p = 0.008) and peripheral tip position (odds ratio 3.82, p = 0.001) were associated with increased infiltration. The probability of infection decreased over time (odds ratio 0.79, p &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122000300_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Peripherally inserted central catheters in paediatric cardiac patients have complication rates similar to other paediatric populations. A prospective assessment of the factors associated with their complications in this patient population may be beneficial in improving outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951122000300","type":"journal-article","created":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T09:24:15Z","timestamp":1644398655000},"page":"79-85","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Complications associated with peripherally inserted central catheters in paediatric cardiac patients"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3968-5268","authenticated-orcid":false,"given":"Jay R.","family":"Patel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpa","family":"Vellore Govardhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1215-3285","authenticated-orcid":false,"given":"Pilar","family":"Anton-Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2022,2,9]]},"reference":[{"key":"S1047951122000300_ref9","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-1577"},{"key":"S1047951122000300_ref21","doi-asserted-by":"crossref","first-page":"557","DOI":"10.5005\/jp-journals-10071-23818","article-title":"Quality improvement initiative to reduce intravenous line-related infiltration and phlebitis incidence in pediatric emergency room","volume":"25","author":"Singh","year":"2021","journal-title":"Indian J Crit Care Med"},{"key":"S1047951122000300_ref27","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2559"},{"key":"S1047951122000300_ref16","doi-asserted-by":"publisher","DOI":"10.1086\/671266"},{"key":"S1047951122000300_ref12","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13950"},{"key":"S1047951122000300_ref3","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1582127"},{"key":"S1047951122000300_ref29","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2003.67"},{"key":"S1047951122000300_ref13","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0529"},{"key":"S1047951122000300_ref20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158045"},{"key":"S1047951122000300_ref19","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.070316"},{"key":"S1047951122000300_ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-021-05019-6"},{"key":"S1047951122000300_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2009.03.015"},{"key":"S1047951122000300_ref1","volume-title":"Percutaneous Central Catheter. 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