{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:47:27Z","timestamp":1786999647208,"version":"build-2736575974"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951122001147_as1\">\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Ventricular septal defect is one of the commonest heart defect in children and closure of this defect with devices has seen a rapid progression over a period of time. The availability of new and safer devices has made the transcatheter closure of ventricular septal defect a suitable option even in young children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951122001147_as2\">\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The study was done to evaluate the feasibility and complications of device closure of ventricular septal defect in children weighing 10 kg or less with different types of devices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951122001147_as3\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The present study was undertaken in a newly established dedicated Paediatric Cardiac Unit at a Tertiary Care Hospital. Relevant data were obtained retrospectively from the case files and the catheterisation records and data were analysed for first 50 patients with ventricular septal defect weighing 10 kg or less between March 2018 and March 2021.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951122001147_as4\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among these 50 patients selected, device closure was successfully done in 45 (90%) cases while 5 (10%) attempts were unsuccessful for various reasons. The mean weight in this study was 7.46 \u00b1 1.89 kg (2.3\u201310 kg), 21 (42%) cases were females while 29 (58%) were males; mean age was 19.4 \u00b1 11.88 months (4\u201348 months). Right heart catheterisation study showed 21 (42%) patients with normal pulmonary artery pressures (no pulmonary artery hypertension). Among 29 patients with pulmonary arterial hypertension, 13 patients (22%) were having mild pulmonary arterial hypertension, 4 (8%) were with moderate pulmonary arterial hypertension, and 12 (24%) were with severe pulmonary arterial hypertension. Mean Qp\/Qs was 2.73 \u00b1 0.72 (2.5\u20134.5) and mean pulmonary vascular resistance was 1.5 \u00b1 1.04 (0.6\u20134.6 WU). Amplatzer Duct Occluder (ADOI) was used in 15 (30%) cases, 27 (52%) cases were closed with Amplatzer Duct Occluder (ADOII), and the 3 (6%) cases closure was done with Amplatzer muscular ventricular septal defect occluder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951122001147_as5\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Transcatheter closure of ventricular septal defect in children 10 kg or less is feasible and safe alternative to surgical ventricular septal defect closure. The immediate and short-term outcomes have proven this method to be safe and valid.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951122001147","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T03:38:54Z","timestamp":1651462734000},"page":"539-545","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Transcatheter closure of ventricular septal defects: preliminary results in children weighing 10 kg or less"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0304-1751","authenticated-orcid":false,"given":"Kamran","family":"Mirza M","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaad","family":"Abqari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azam","family":"Haseen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayank","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,5,2]]},"reference":[{"key":"S1047951122001147_ref17","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20659"},{"key":"S1047951122001147_ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-011-0155-z"},{"key":"S1047951122001147_ref16","first-page":"941","article-title":"Percutaneous closure of perimembranous ventricular septal defects with Amplatzer occluders\u2013a single centre experience","volume":"66","author":"Szkutnik","year":"2008","journal-title":"Kardiol Pol"},{"key":"S1047951122001147_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-018-1852-5"},{"key":"S1047951122001147_ref1","first-page":"446","article-title":"The results of direct vision closure of ventricular septal defects in eight patients by means of controlled cross circulation","volume":"101","author":"Lillehei","year":"1955","journal-title":"Surg Gynecol Obstet"},{"key":"S1047951122001147_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.12.011"},{"key":"S1047951122001147_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-007-9092-0"},{"key":"S1047951122001147_ref18","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20512"},{"key":"S1047951122001147_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.12.050"},{"key":"S1047951122001147_ref22","doi-asserted-by":"publisher","DOI":"10.5812\/ijp.386"},{"key":"S1047951122001147_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26097"},{"key":"S1047951122001147_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.02.037"},{"key":"S1047951122001147_ref14","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.084988"},{"key":"S1047951122001147_ref5","first-page":"479","article-title":"ADO II in percutaneous VSD closure in pediatric patients","volume":"28","author":"Narin","year":"2015","journal-title":"J IntervCardiol"},{"key":"S1047951122001147_ref8","article-title":"Treatment of congenital non-ductal shunt lesions with the Amplatzer Duct Occluder II","author":"Vijayalakshmi","year":"2013","journal-title":"Catheter Cardiovasc Interv"},{"key":"S1047951122001147_ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-014-1017-0"},{"key":"S1047951122001147_ref23","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951117002396"},{"key":"S1047951122001147_ref24","doi-asserted-by":"publisher","DOI":"10.1017\/S104795111700107X"},{"key":"S1047951122001147_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20499"},{"key":"S1047951122001147_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.10.047"},{"key":"S1047951122001147_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.068"},{"key":"S1047951122001147_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm314"},{"key":"S1047951122001147_ref19","article-title":"Late complete heart block in an adult patient undergoing percutaneous ventricular septal defect closure","volume":"20","author":"Collins","year":"2008","journal-title":"J Invasive Cardiol"},{"key":"S1047951122001147_ref7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1046\/j.1540-8183.2003.08006.x","article-title":"Transcatheter closure of congenital ventricular septal defects: experience with various devices","volume":"16","author":"Trehan","year":"2003","journal-title":"J Interv Cardiol"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951122001147","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T19:24:32Z","timestamp":1684178672000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951122001147\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,2]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S1047951122001147"],"URL":"https:\/\/doi.org\/10.1017\/s1047951122001147","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,2]]},"assertion":[{"value":"\u00a9 The Author(s), 2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}