{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T18:21:01Z","timestamp":1784830861810,"version":"3.55.0"},"reference-count":31,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T00:00:00Z","timestamp":1655078400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951122001305_as1\"><jats:title>Background:<\/jats:title><jats:p>Nutritional assessment appears to be an essential component of the evaluation of children with CHD undergoing surgery because nutritional status may impact corrective surgery-associated morbidity.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122001305_as2\"><jats:title>Methods:<\/jats:title><jats:p>A prospective single-centre cohort study with children between 6 and 24 months of age. Patients who had genetic syndromes or those who were premature or low birthweight at birth were excluded. Pre-operative nutritional parameters included anthropometric measurements and serum concentrations of total protein, vitamin D, iron, and ferritin. Outcome measures included ICU length of stay, mechanical ventilation, vasoactive-inotropic score, and duration of inotropes. Linear regression analysis was performed to determine whether pre-operative variables were associated with outcomes.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122001305_as3\"><jats:title>Results:<\/jats:title><jats:p>Analysis was performed on 120 patients (median age of 8 months), of whom 67 were male. Prior to surgery, 50.8% of patients had reduced (z\u00a0\u2264\u00a0\u22122.0) weight-for-age z score, 23.3% had reduced length-for-age z score, and 59.2% had reduced mid-upper arm circumference z score. Pre-operative serum total protein levels were 59.36\u00a0\u00b1\u00a09.16\u00a0g\/L. Multiple regression analysis showed that low serum protein was associated with longer ICU length of stay and length of mechanical ventilation, while mid-upper arm circumference z score\u00a0\u2264\u00a0\u22122 was associated with longer ICU length of stay and mechanical ventilation and inotropes duration.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122001305_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Pre-operative assessment of nutritional status by performing anthropometric and biochemical measurements including mid-upper arm circumference z score and serum protein concentrations in children undergoing CHD surgery appears to be predictors of some post-operative short-term outcomes and could be used as a guide to highlight patients needing appropriate perioperative nutritional interventions.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951122001305","type":"journal-article","created":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T11:45:57Z","timestamp":1655120757000},"page":"579-589","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Pre-operative nutritional status and its association with short-term post-operative outcomes in Iranian children with CHD"],"prefix":"10.1017","volume":"33","author":[{"given":"Maryam","family":"Aryafar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Mahdavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Shahzadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Gabeleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9133-1870","authenticated-orcid":false,"given":"Javad","family":"Nasrollahzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,6,13]]},"reference":[{"key":"S1047951122001305_ref27","first-page":"271","article-title":"Should we change reference range for serum albumin in major gastrointestinal surgery? 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