{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:14:10Z","timestamp":1785284050208,"version":"3.55.0"},"reference-count":31,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T00:00:00Z","timestamp":1666656000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951122003274_as1\"><jats:title>Background:<\/jats:title><jats:p>Assessing the hepatic status of children with CHD is very important in the post-operative period. This study aimed to assess the usefulness of paediatric liver T1\/T2 values and to evaluate the impact of respiration on liver T1\/T2 values.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003274_as2\"><jats:title>Methods:<\/jats:title><jats:p>Liver T1\/T2 values were evaluated in 69 individuals who underwent cardiac MRI. The mean age of the participants was 16.2 \u00b1 9.8 years. Two types of imaging with different breathing methods were possible in 34 participants for liver T1 values and 10 participants for liver T2 values.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003274_as3\"><jats:title>Results:<\/jats:title><jats:p>The normal range was set at 620\u2013830 msec for liver T1 and 25\u201340 ms for liver T2 based on the data obtained from 17 healthy individuals. The liver T1\/T2 values were not significantly different between breath-hold and free-breath imaging (T1: 769.4 \u00b1 102.8 ms versus 763.2 \u00b1 93.9 ms; p = 0.148, T2: 34.9 \u00b1 4.0 ms versus 33.6 \u00b1 2.4 ms; p = 0.169). Higher liver T1 values were observed in patients who had undergone Fontan operation, tetralogy of Fallot operation, or those with chronic viral hepatitis. There was a trend toward correlation between liver T1 values and liver stiffness (R = 0.65, p = 0.0004); and the liver T1 values showed a positive correlation with the shear wave velocity (R = 0.62, p = 0.0006).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003274_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Liver T1\/T2 values were not affected by breathing patterns. Because liver T1 values tend to increase with right heart overload, evaluation of liver T1 values during routine cardiac MRI may enable early detection of future complications.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951122003274","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T10:13:51Z","timestamp":1666692831000},"page":"1859-1865","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Liver T1\/T2 values with cardiac MRI during respiration"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8701-826X","authenticated-orcid":false,"given":"Hideharu","family":"Oka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouichi","family":"Nakau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadahiro","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rina","family":"Imanishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorachi","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Mikami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Fukao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunihiro","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,10,25]]},"reference":[{"key":"S1047951122003274_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.04.032"},{"key":"S1047951122003274_ref12","first-page":"S1076-6332(21)00432-3","article-title":"Feasibility of Hepatic T1-mapping and extracellular volume quantification on routine cardiac magnetic resonance imaging in patients with infiltrative and systemic disorders","volume":"29","author":"Dolan","year":"2021","journal-title":"Acad Radiol"},{"key":"S1047951122003274_ref2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-17-1053"},{"key":"S1047951122003274_ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-020-04805-y"},{"key":"S1047951122003274_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-019-04411-7"},{"key":"S1047951122003274_ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-020-02822-x"},{"key":"S1047951122003274_ref13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.117.007241"},{"key":"S1047951122003274_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2020.12.005"},{"key":"S1047951122003274_ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3994-7"},{"key":"S1047951122003274_ref29","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-018-1528-x"},{"key":"S1047951122003274_ref20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-74717-2"},{"key":"S1047951122003274_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-019-01990-9"},{"key":"S1047951122003274_ref30","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2020-001434"},{"key":"S1047951122003274_ref1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.13.3.273"},{"key":"S1047951122003274_ref8","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-15-0054"},{"key":"S1047951122003274_ref15","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.19.22009"},{"key":"S1047951122003274_ref11","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.mp.2020-0063"},{"key":"S1047951122003274_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07080-5"},{"key":"S1047951122003274_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15812"},{"key":"S1047951122003274_ref17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-44377-y"},{"key":"S1047951122003274_ref31","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines8100412"},{"key":"S1047951122003274_ref27","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-021-00598-0"},{"key":"S1047951122003274_ref7","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-15-92"},{"key":"S1047951122003274_ref5","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-22-0134"},{"key":"S1047951122003274_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-020-02684-3"},{"key":"S1047951122003274_ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-020-02520-8"},{"key":"S1047951122003274_ref28","first-page":"1","article-title":"Comparison of myocardial T1 mapping during breath-holding and free-breathing","volume":"32","author":"Oka","year":"2021","journal-title":"Cardiol Young"},{"key":"S1047951122003274_ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-020-04663-8"},{"key":"S1047951122003274_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-020-02533-6"},{"key":"S1047951122003274_ref21","doi-asserted-by":"publisher","DOI":"10.5152\/dir.2020.19654"},{"key":"S1047951122003274_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2015.05.019"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951122003274","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T10:17:26Z","timestamp":1697019446000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951122003274\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,25]]},"references-count":31,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S1047951122003274"],"URL":"https:\/\/doi.org\/10.1017\/s1047951122003274","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,25]]},"assertion":[{"value":"\u00a9 The Author(s), 2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}