{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T01:41:57Z","timestamp":1784770917161,"version":"3.55.0"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951122003547_as1\"><jats:title>Background:<\/jats:title><jats:p>Transcatheter closure of perimembranous ventricular septal defects is challenging. Double disk-designed devices have high adverse event rates; therefore, research into new devices persists. One such devise is the LifetechTM Konar-MF Occluder device (MFO), which is increasingly used. The purpose of this study is to present mid-term results of MFO for transcatheter closure of patients with perimembraneous ventricular septal defect.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003547_as2\"><jats:title>Patients and methods:<\/jats:title><jats:p>Records of the 52 patients with perimembraneous ventricular septal defect who had undergone transcatheter closure with MFO were reviewed. Demographic, echocardiographic, and procedure details were investigated. Three years follow-up results were recorded.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003547_as3\"><jats:title>Results:<\/jats:title><jats:p>We closed the perimembraneous ventricular septal defect in 51 of 52 patients (98%). The femoral venous approach was used in 27 patients (53 %) whilst no arteriovenous loop was established in the remaining patients. No significant procedure-related complication occurred. On day 1 echocardiography, the residual ventricular septal defect rate was 31%. Mean\u00b1SD (range) follow-up duration was 36 \u00b1 7,9 (18\u201354) months. In the follow-up, at 6th months, only four patients had hemodynamically insignificant residual defects. No severe dysrhythmia was detected including complete heart block. A right bundle branch block pattern was seen in one patient.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003547_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>This study showed that MFO is a safe and effective device in the transcatheter treatment of perimembraneous ventricular septal defect\u2019s with mid-term follow-up.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951122003547","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T05:38:04Z","timestamp":1668577084000},"page":"2021-2026","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Early and mid-term outcomes of transcatheter closure of perimembranous ventricular septal defects using the Lifetech\u2122 Konar-MF Occluder device (MFO)"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1041-6299","authenticated-orcid":false,"given":"Ender","family":"Odemis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mete Han","family":"Kizilkaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,11,16]]},"reference":[{"key":"S1047951122003547_ref2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10797"},{"key":"S1047951122003547_ref19","first-page":"402","article-title":"Transcatheter closure of postoperative residual ventricular septal defects using Amplatzer-type perimembranous VSD occluders","volume":"8","author":"Zhang","year":"2013","journal-title":"J Invasive Cardiol"},{"key":"S1047951122003547_ref21","first-page":"113","article-title":"Transcatheter closure of a perimembranous ventricular septal defect with Nit-Occlud L\u00ea VSD Coil: a French multicentre study","volume":"2","author":"Houeijeh","year":"2020","journal-title":"Arch Cardiovasc Dis"},{"key":"S1047951122003547_ref6","first-page":"1","article-title":"Percutaneous closure of ventricular septal defect using LifeTechTM Konar-MF VSD Occluder: initial and short-term multiinstitutional results","author":"Sadiq","year":"2021","journal-title":"Cardiol Young"},{"key":"S1047951122003547_ref10","first-page":"461","article-title":"Directly ventricular septal defect closure without using arteriovenous wire loop: our adult case series using transarterial retrograde approach","volume":"6","author":"Pekel","year":"2017","journal-title":"Anatol J Cardiol"},{"key":"S1047951122003547_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.recesp.2020.05.018"},{"key":"S1047951122003547_ref22","first-page":"19(e20120)","article-title":"Very late-onset endocarditis complicated by non-significant aortic regurgitation after device closure of perimembranous ventricular 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device closure of perimembranous ventricular septal defect associated with indirect Gerbode defect: a retrospective study","volume":"3","author":"Parvez","year":"2021","journal-title":"Ann Pediatr Cardiol"},{"key":"S1047951122003547_ref20","doi-asserted-by":"publisher","DOI":"10.1177\/2150135119825562"},{"key":"S1047951122003547_ref15","first-page":"6646482","article-title":"Transcatheter closure of perimembranous ventricular septal defect with aneurysm: radiologic characteristic and interventional strategy","volume":"24","author":"Guo","year":"2020","journal-title":"J Interv Cardiol"}],"updated-by":[{"DOI":"10.1017\/s1047951122003778","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000}}],"container-title":["Cardiology in the 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The Author(s), 2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}