{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:58:00Z","timestamp":1747173480504,"version":"3.40.5"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T00:00:00Z","timestamp":1670976000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951122003900_as1\"><jats:title>Background:<\/jats:title><jats:p>Paediatric studies have shown serum N-terminal pro b-type natriuretic peptide levels to be a valuable tool in the surveillance of myocardial function and an early biomarker for rejection in transplant patients. The correlation between low mean right atrial pressure and increased inferior vena cava collapsibility index is well studied in adults. Our study aims to assess correlation between non-invasive measurements (serum N-terminal pro b-type natriuretic peptide, inferior vena cava dimensions collapsibility, tricuspid regurgitation, and left ventricular remodelling index to invasive mean right atrial pressure in paediatric heart transplant patients).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003900_as2\"><jats:title>Methods:<\/jats:title><jats:p>A single centre, retrospective chart review of the paediatric transplant patients from 0 to 21 years of age was performed between 2015 and 2017. Thirty-nine patients had complete data which includes cardiac catheterisation, transthoracic echocardiogram, and serum N-terminal pro b-type natriuretic peptide levels done within a two weeks of interval.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003900_as3\"><jats:title>Results:<\/jats:title><jats:p>A higher inferior vena cava collapsibility index correlated with a lower mean right atrial pressure (r = \u22120.21, p = 0.04) and a larger inferior vena cava diameter in expiration indexed to body surface area (IVCmax\/BSA0.5) correlated with a higher mean right atrial pressure (r = 0.29, p = 0.01). There was a correlation between elevated N-terminal pro b-type natriuretic peptide and inferior vena cava collapsibility index (r = \u22120.38, p = 0.0001), IVCmax\/BSA0.5 (r = 0.25, p = 0.0002), and mean right atrial pressure (r = 0.6, p = 0.0001).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951122003900_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Serum N-terminal pro b-type natriuretic peptide levels correlated to non-invasive measurements (inferior vena cava collapsibility index and IVCmax\/BSA<jats:sup>0.5<\/jats:sup>) and to the invasive mean right atrial pressure. Non-invasive (IVC-CI IVCmax\/BSA<jats:sup>0.5<\/jats:sup>) correlates with elevated mean right atrial pressure in this population. Together, these may serve as a reliable surveillance tool in assessing right heart filling pressures and cardiac function within the paediatric heart transplant patient.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951122003900","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T09:19:03Z","timestamp":1671009543000},"page":"2034-2040","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Correlation between non-invasive to invasive right-heart data in paediatric heart transplant patients"],"prefix":"10.1017","volume":"33","author":[{"given":"Mark","family":"McGill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9409-9560","authenticated-orcid":false,"given":"Kishore 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}