{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:40:41Z","timestamp":1778542841857,"version":"3.51.4"},"reference-count":28,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123000021_as1\"><jats:title>Background:<\/jats:title><jats:p>Balloon valvuloplasty is the primary treatment for congenital aortic valve stenosis in our centre. We sought to determine independent predictors of reintervention (surgical repair or repeated balloon dilation) after primary valvuloplasty.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000021_as2\"><jats:title>Methods:<\/jats:title><jats:p>We retrospectively studied patients with congenital aortic valve stenosis who underwent balloon valvuloplasty during 2004\u20132018. The following risk factors were analysed: aortic valve insufficiency after balloon valvuloplasty &gt;+1\/4, post-procedural gradient across the aortic valve \u226535 mmHg, pre-interventional gradient across the valve, annulus size, use of rapid pacing, and balloon\/annulus ratio. Primary outcome was aortic valve reintervention.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000021_as3\"><jats:title>Results:<\/jats:title><jats:p>In total, 99 patients (median age 4 years, range 1 day to 26 years) underwent balloon valvuloplasty for congenital aortic valve stenosis. After a mean follow-up of 4.0 years, 30% had reintervention. Adjusted risks for reintervention were significantly increased in patients with post-procedural aortic insufficiency grade &gt;+1\/4 and\/or residual gradient \u226535 mmHg (HR 2.55, 95% CI 1.13\u20135.75, p = 0.024). Pre-interventional gradient, annulus size, rapid pacing, and balloon\/annulus ratio were not associated with outcome.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000021_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Post-procedural aortic valve insufficiency grade &gt;+1\/4 and\/or residual gradient \u226535 mmHg in patients undergoing balloon valvuloplasty for congenital aortic valve stenosis confers an increased risk for reintervention in mid-term follow-up.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123000021","type":"journal-article","created":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T09:30:45Z","timestamp":1674120645000},"page":"2267-2273","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Immediate results of primary balloon dilation for congenital aortic valve stenosis predict the mid-term outcome"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1206-1970","authenticated-orcid":false,"given":"Andrija","family":"Pavlovic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vojislav","family":"Parezanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor","family":"Stefanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"D\u00e4hnert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aphrodite","family":"Tzifa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan 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balloon aortic valvuloplasty effectively delays surgical intervention in children with recurrent aortic stenosis","volume":"82","author":"Petit","year":"2013","journal-title":"Catheter Cardiovasc Interv"},{"key":"S1047951123000021_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951114001085"},{"key":"S1047951123000021_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.07.052"},{"key":"S1047951123000021_ref17","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.73.3.452"},{"key":"S1047951123000021_ref16","first-page":"340","volume-title":"Echocardiography in Pediatric and Congenital Heart Disease: From Fetus to 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}