{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:47:27Z","timestamp":1790275647032,"version":"4.1.0"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T00:00:00Z","timestamp":1674432000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123000100_as1\"><jats:title>Objectives:<\/jats:title><jats:p>Cardiac manifestations of the coronavirus disease 2019 (COVID-19) have mainly been reported in adults. Therefore, we aimed to determine the electrocardiographic abnormalities in hospitalised paediatric patients with COVID-19 and multisystemic inflammatory syndrome in children.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000100_as2\"><jats:title>Methods:<\/jats:title><jats:p>We retrospectively evaluated hospitalised paediatric patients &lt;18 years of age with a diagnosis of COVID-19 (n = 168) and multisystem inflammatory syndrome in children (n = 48) between March 2021 and December 2021. A daily electrocardiography was performed for the patients who had electrocardiographic abnormalities on admission or developed electrocardiographic abnormality on the follow-up. The characteristics of these patients, underlying predisposing conditions, and clinical course were also examined.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000100_as3\"><jats:title>Results:<\/jats:title><jats:p>Two-hundred sixteen paediatric patients (55% were male) with a mean age of 10.7 \u00b1 4.69 years were evaluated. There was an underlying disease in 84 (38.8%) patients and 51 (23.6%) required paediatric ICU admission. Electrocardiography abnormality was detected in 12 (5.5%) which were as follows: 7 (3.2%) had sinus bradycardia, 3 (1.4%) patients had transient ST elevation and concomitant T negativity, and 2 (0.9%) developed first-degree Atrioventricular (AV) block. The median time from the onset of disease symptoms to detecting electrocardiographic abnormality was 9 days. Electrocardiographic abnormalities returned to normal uneventfully 3 days later.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000100_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>The prevalence of arrhythmia in paediatric patients with COVID-19 was detected in 5.5% of the patients. While two-thirds of the electrocardiography abnormalities were sinus bradycardia, ST elevation was remarkable (1.4%). Clinicians should be aware of electrocardiographic abnormalities and consider electrocardiographic monitoring in paediatric patients with COVID-19 and multisystemic inflammatory syndrome in children.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123000100","type":"journal-article","created":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T09:45:40Z","timestamp":1674467140000},"page":"525-531","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Electrocardiographic changes in hospitalised children with COVID-19"],"prefix":"10.1017","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0562-3544","authenticated-orcid":false,"given":"Gulhadiye","family":"Avcu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asl\u0131","family":"Arslan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9189-8220","authenticated-orcid":false,"given":"Zumrut Sahbudak","family":"Bal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oguzhan","family":"Ay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erturk","family":"Levent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferda","family":"Ozkinay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zafer","family":"Kurugol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,1,23]]},"reference":[{"key":"S1047951123000100_ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-020-03766-6"},{"key":"S1047951123000100_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31103-X"},{"key":"S1047951123000100_ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2020.08.025"},{"key":"S1047951123000100_ref26","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd8020018"},{"key":"S1047951123000100_ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.1017"},{"key":"S1047951123000100_ref1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-0702"},{"key":"S1047951123000100_ref7","first-page":"1","article-title":"Complete heart block, severe right ventricular dysfunction in a child with COVID-19 infection","volume":"4","author":"Sisko","year":"2021","journal-title":"Cardiol Young"},{"key":"S1047951123000100_ref31","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4167-1"},{"key":"S1047951123000100_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.11.011"},{"key":"S1047951123000100_ref24","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytab405"},{"key":"S1047951123000100_ref28","unstructured":"28. US Food and Drug Administration (FDA) approves the first COVID-19 treatment for young children. The latest Updates and Resources on Novel Coronavirus (COVID-19). https:\/\/www.aha.org\/news\/news\/2022-04-25-fda-approves-first-covid-19-treatment-youngchildren#:\u223c:text=The%20Food%20and%20Drug%20Administration,progressing%20to%20severe%20COVID%2D19"},{"key":"S1047951123000100_ref2","unstructured":"2. Centers for Disease Control and Prevention. Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19), 2020. 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Retrieved October 22, 2020, from https:\/\/emergency.cdc.gov\/han\/2020\/han00432.asp"},{"key":"S1047951123000100_ref17","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14042"},{"key":"S1047951123000100_ref13","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1007\/s00134-020-05991-x","article-title":"Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China","volume":"46","author":"Ruan","year":"2020","journal-title":"Intensive Care Med"},{"key":"S1047951123000100_ref27","unstructured":"27. US Food and Drug Administration (FDA). Frequently asked questions on the Emergency Use Authorization for Veklury\u00ae (remdesivir) for hospitalized COVID-19 patients, October 22, 2020. 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}