{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:58:08Z","timestamp":1747173488161,"version":"3.40.5"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123000239_as1\"><jats:title>Background:<\/jats:title><jats:p>Right ventricle dysfunction is common after corrective surgery for tetralogy of Fallot and is associated with significant morbidity and mortality. We aimed to determine whether an increased portal vein pulsatility fraction (PVPF) was associated with worse clinical outcomes.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000239_as2\"><jats:title>Methods:<\/jats:title><jats:p>In a prospective, observational, single-centre study, PVPF and other commonly used parameters of right ventricle function were assessed in patients of all ages undergoing corrective surgery for tetralogy of Fallot intraoperatively, with transesophageal echocardiography, before and after bypass, and post-operatively, with transthoracic echocardiography, at days 1, 2, at extubation, and at ICU discharge. The correlation was tested between PVPF and mechanical ventilation duration, prolonged ICU stay, mortality, and right ventricle function.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000239_as3\"><jats:title>Results:<\/jats:title><jats:p>The study included 52 patients, and mortality was in 3 patients. PVPF measurement was feasible in 96% of the examinations. PVPF in the immediate post-operative period had sensitivity of 73.3% and a specificity of 74.3% in predicting the occurrence of the composite outcome of prolonged mechanical ventilation, ICU stay, or mortality. There was a moderate negative correlation of PVPF with right ventricle fractional area change and right ventricle global longitudinal strain (r = \u22120.577, p &lt; 0.001 and r = 0.465, p &lt; 0.001, respectively) and a strong positive correlation with abnormal hepatic vein waveform (rho = 0.749, p &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123000239_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>PVPF is an easily obtainable bedside parameter to assess right ventricular dysfunction and predict prolonged mechanical ventilation, prolonged ICU stay, and mortality.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123000239","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T08:13:35Z","timestamp":1678695215000},"page":"2357-2362","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Utility of portal vein pulsatility fraction in patients undergoing corrective surgery for tetralogy of Fallot"],"prefix":"10.1017","volume":"33","author":[{"given":"Hiteshi","family":"Aggarwal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9984-7150","authenticated-orcid":false,"given":"Rajarajan","family":"Ganesan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6758-5926","authenticated-orcid":false,"given":"Banashree","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit M.","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9635-0977","authenticated-orcid":false,"given":"Vidur","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam K.S.","family":"Thingnam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9763-4055","authenticated-orcid":false,"given":"Goverdhan Dutt","family":"Puri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2023,3,13]]},"reference":[{"key":"S1047951123000239_ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2007.00424.x"},{"key":"S1047951123000239_ref11","first-page":"1","article-title":"Utility of Doppler ultrasound derived hepatic and portal venous waveforms in the management of heart failure exacerbation","volume":"00","author":"Singh","year":"2020","journal-title":"Clin Case Rep"},{"key":"S1047951123000239_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-008-9314-4"},{"key":"S1047951123000239_ref19","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10071-23570"},{"key":"S1047951123000239_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2018.09.028"},{"key":"S1047951123000239_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(97)00272-X"},{"key":"S1047951123000239_ref9","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i5.768"},{"key":"S1047951123000239_ref18","first-page":"e20545","article-title":"Perioperative venous excess ultrasound score (VExUS) to guide decongestion in a dilated cardiomyopathy patient presenting for urgent surgery","volume":"13","author":"Singh","year":"2021","journal-title":"Cureus"},{"key":"S1047951123000239_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2012.05.011"},{"key":"S1047951123000239_ref5","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.009961"},{"key":"S1047951123000239_ref13","doi-asserted-by":"crossref","first-page":"39","DOI":"10.4103\/aca.ACA_250_18","article-title":"Portal venous pulsatility fraction, a novel transesophageal echocardiographic marker for right ventricular dysfunction in cardiac surgical patients","volume":"23","author":"Singh","year":"2020","journal-title":"Ann Card Anaesth."},{"key":"S1047951123000239_ref1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-019-0909-8"},{"key":"S1047951123000239_ref12","doi-asserted-by":"publisher","DOI":"10.1186\/cc2872"},{"key":"S1047951123000239_ref3","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31818d8b92"},{"key":"S1047951123000239_ref14","unstructured":"14. Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography Endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography,"},{"key":"S1047951123000239_ref6","first-page":"635e9","article-title":"Changes of portal flow in heart failure patients with liver congestion","volume":"111","author":"Goncalvesova","year":"2010","journal-title":"Bratisl Lek Listy"},{"key":"S1047951123000239_ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s13089-021-00232-8"},{"key":"S1047951123000239_ref4","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2017.11.030"},{"key":"S1047951123000239_ref7","doi-asserted-by":"publisher","DOI":"10.1148\/rg.311105093"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951123000239","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T09:35:30Z","timestamp":1711445730000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951123000239\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,13]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S1047951123000239"],"URL":"https:\/\/doi.org\/10.1017\/s1047951123000239","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2023,3,13]]},"assertion":[{"value":"\u00a9 The Author(s), 2023. 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