{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:58:37Z","timestamp":1747173517943,"version":"3.40.5"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:00:00Z","timestamp":1695600000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123003244_as1\"><jats:title>Background:<\/jats:title><jats:p>The Fontan procedure is considered one of the most remarkable achievements in paediatric cardiology and cardiac surgery. Its final anatomical objective is a venous return through the superior and inferior vena cava. The complications inherent to this procedure and subsequent failure are its limitations.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003244_as2\"><jats:title>Objective:<\/jats:title><jats:p>To describe the clinical and haemodynamic characteristics of patients with Fontan failure and define the risk factors associated with it, with its short- and long-term outcomes during a 21-year observation period.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003244_as3\"><jats:title>Methods:<\/jats:title><jats:p>This is a retrospective follow-up study in which 15 patients diagnosed with Fontan failure in the single-ventricle programme of a high-complexity hospital in Medell\u00edn, Colombia, between 2001 and 2022 were included.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003244_as4\"><jats:title>Results:<\/jats:title><jats:p>One hundred and eight patients were identified in whom the Fontan procedure was performed, and 17 met the failure criteria. 82.4% were men, with a median age of 4.3 years. Ebstein\u2019s anomaly was the most common diagnosis, 29.4%. All patients underwent Fontan with an extracardiac tube following the procedure. According to the type of failure, 58.8% of patients presented protein-losing enteropathy and 17.6% plastic bronchitis. During follow-up, 5.9% of patients died.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003244_as5\"><jats:title>Conclusion:<\/jats:title><jats:p>Fontan surgery in our centre is an option for patients with univentricular physiology. The correct selection of the patient is essential to mitigate failure risks.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123003244","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T07:37:06Z","timestamp":1695627426000},"page":"722-726","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Fontan surgery failure: risk factors and experience in a Colombian reference centre"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4980-892X","authenticated-orcid":false,"given":"Isabel C.","family":"S\u00e1nchez-Escobar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0867-4793","authenticated-orcid":false,"given":"Andr\u00e9s D.","family":"Aranzazu-Ceballos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9054-847X","authenticated-orcid":false,"given":"Luz E.","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1716-1999","authenticated-orcid":false,"given":"M\u00f3nica I.","family":"Guzm\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2023,9,25]]},"reference":[{"key":"S1047951123003244_ref8","first-page":"91","article-title":"Fontan surgery: postsurgical complications: Medell\u00edn, Colombia \/ Fontan surgery: complications postsurgical","volume":"85","author":"Vargas","year":"2014","journal-title":"Arch Pediatrics Urug"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref17","DOI":"10.1017\/S1047951122001433"},{"key":"S1047951123003244_ref10","first-page":"425","article-title":"Fontan surgery: risk factors in the short and medium term","volume":"75","author":"Calder\u00f3n-Colmenero","year":"2005","journal-title":"Arch Cardiol Mex"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref2","DOI":"10.1007\/s12098-015-1803-6"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref12","DOI":"10.1017\/S104795111900221X"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref1","DOI":"10.1016\/S0300-8932(02)76619-0"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref4","DOI":"10.1016\/j.jacc.2005.12.065"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref14","DOI":"10.1016\/S0022-5223(98)70406-4"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref3","DOI":"10.1111\/chd.12368"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref5","DOI":"10.1016\/j.jacc.2012.05.010"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref7","DOI":"10.1093\/ejcts\/ezu489"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref13","DOI":"10.1017\/S1047951101000312"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref16","DOI":"10.1016\/j.cjca.2022.04.014"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref6","DOI":"10.1016\/j.ejcts.2006.11.043"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref9","DOI":"10.1016\/j.jacc.2015.07.065"},{"key":"S1047951123003244_ref11","first-page":"1","article-title":"Comparison of patients undergoing Fontan surgery with and without cardiopulmonary bypass","volume":"86","author":"Ortiz-V\u00e1zquez","year":"2016","journal-title":"Arch Cardiol Mex"},{"doi-asserted-by":"publisher","key":"S1047951123003244_ref15","DOI":"10.1016\/j.jpeds.2014.12.068"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951123003244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T11:31:39Z","timestamp":1713180699000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951123003244\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,25]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S1047951123003244"],"URL":"https:\/\/doi.org\/10.1017\/s1047951123003244","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2023,9,25]]},"assertion":[{"value":"\u00a9 The Author(s), 2023. 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