{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:58:42Z","timestamp":1747173522871,"version":"3.40.5"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T00:00:00Z","timestamp":1698019200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123003621_as1\"><jats:title>Introduction:<\/jats:title><jats:p>Physical activity is recognised as an important intervention in patients with CHD. However, more data on the actual magnitude of physical training impact on functional capacity in this group of patients are still warranted. We aim to assess effort tolerance in a contemporary cohort of patients with congenital heart disease, regularly following a training programme, in comparison with a matched control group.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003621_as2\"><jats:title>Methods:<\/jats:title><jats:p>Patients with CHD followed at the sports medicine department, who had undergone cardiopulmonary exercise test between 2011 and 2019, were included. Variables recorded were maximum workload, absolute and indexed maximum oxygen consumption, maximum heart rate, absolute and indexed maximum O2 pulse, ventilatory equivalent of CO2 and oxygen consumption\/Work. Trend of cardiopulmonary parameters was analysed over time. Maximal workload, maximum oxygen consumption and ventilatory equivalent of CO2 were compared with a control group of patients with a more sedentary lifestyle, matched for diagnosis, gender, age, and body mass index.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003621_as3\"><jats:title>Results:<\/jats:title><jats:p>Among one hundred and eleven patients, 73 males (66%) were analysed. Median age was 14 (12\u201317) years. Twenty-nine patients (27%) were practising sports at competitive level. Maximum oxygen consumption and oxygen consumption % of maximum predicted were not significantly different at follow-up as compared with baseline. Follow-up of maximum oxygen consumption was 38.2 \u00b1 9 ml\/kg\/min versus 38.6 \u00b1 9.2 ml\/kg\/min (p = NS) and follow-up of %oxygen consumption was 88 \u00b1 20 versus 87 \u00b1 15 (p = NS). Ventilatory equivalent of CO2 significantly improved in the last test as compared with the baseline: 30 \u00b1 4 versus 33 \u00b1 5 (p = 0.002). As compared with the control group, trained patients displayed a significantly higher maximum workload and oxygen consumption, while ventilatory equivalent of CO2 was not significantly different.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003621_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>In our cohort, patients following a regular training programme displayed a significantly higher functional capacity as compared with not trained control group, irrespective of NYHA class. Objective functional capacity was stable over a median follow-up of 3 years.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123003621","type":"journal-article","created":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T08:48:39Z","timestamp":1698050919000},"page":"831-837","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Long-term effects of physical training on cardiopulmonary exercise parameters in young patients with congenital heart diseases"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7967-7417","authenticated-orcid":false,"given":"Paolo","family":"Ferrero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Piazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Poggioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Chessa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Lorenzelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2023,10,23]]},"reference":[{"key":"S1047951123003621_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.529800"},{"key":"S1047951123003621_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-015-3299-1"},{"key":"S1047951123003621_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.02.081"},{"key":"S1047951123003621_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0803.2008.00191.x"},{"key":"S1047951123003621_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi396"},{"key":"S1047951123003621_ref8","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951100006557"},{"key":"S1047951123003621_ref13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.058719"},{"key":"S1047951123003621_ref14","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e31827b0b20"},{"key":"S1047951123003621_ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.159.11.1063"},{"key":"S1047951123003621_ref9","first-page":"2085","article-title":"Effect of physical training on children after reconstructive heart surgery","volume":"131","author":"Peja","year":"1990","journal-title":"Orv Hetil"},{"key":"S1047951123003621_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.958025"},{"key":"S1047951123003621_ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.784648"},{"key":"S1047951123003621_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.07.092"},{"key":"S1047951123003621_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.05.086"},{"key":"S1047951123003621_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2015.06.018"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951123003621","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T11:31:36Z","timestamp":1713180696000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951123003621\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,23]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S1047951123003621"],"URL":"https:\/\/doi.org\/10.1017\/s1047951123003621","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2023,10,23]]},"assertion":[{"value":"\u00a9 The Author(s), 2023. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}