{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T20:35:16Z","timestamp":1783629316267,"version":"3.55.0"},"reference-count":7,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T00:00:00Z","timestamp":1702857600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123003669_as1\"><jats:title>Introduction:<\/jats:title><jats:p>Congenital junctional ectopic tachycardia is a rare arrhythmia that occurs in patients without previous cardiac surgery. In this report, we wanted to present a 6-hour-old newborn with congenital junctional ectopic tachycardia resistant to conventional anti-arrhythmic medications, who was successfully treated with ivabradine and amiadarone combination.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003669_as2\"><jats:title>Case:<\/jats:title><jats:p>A six-hour-old newborn girl was hospitalised in neonatal ICU because transient tachypnoea of the newborn. She was tachycardic, and supraventricular tachycardia was noticed. There was no answer to the adenosine esmolol treatment; even synchronised direct cardioversion intravenous amiodarone was started. Junctional ectopic tachycardia was diagnosed. We have added propranolol to the treatment and followed patient for 2 days. On the fourth day, junctional ectopic tachycardia rhythm still persisted; therefore, ivabradine treatment was added to the treatment. On the following day, the heart rhythm was slowed to 110\/min, and propranolol was stopped; intravenous amiodarone treatment was changed to the oral form. The rhythm turned into sinus; two days after starting ivabradine and oral amiodarone.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003669_as3\"><jats:title>Conclusion:<\/jats:title><jats:p>Tachyarrhythmia originating in the atrioventricular node and atrioventricular junction including the bundle of His complex are junctional ectopic tachycardia. Congenital junctional ectopic tachycardia is rare, and it is mostly resistant to the conventional treatment.<\/jats:p><jats:p>Ivabradine is a new anti-arrhythmic agent, used extensively to decrease sinus rate in the treatment of cardiac failure. Ivabradine may be an option for the resistant congenital ectopic tachycardia<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123003669","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T06:40:08Z","timestamp":1702881608000},"page":"445-447","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Ivabradine for congenital ectopic tachycardia in newborn"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3321-2387","authenticated-orcid":false,"given":"Ozge","family":"Pamukcu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00fcmeysa","family":"Citli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,12,18]]},"reference":[{"key":"S1047951123003669_ref3","first-page":"163","volume-title":"Josephson\u2019s Clinical Cardiac Electrophysiology: Techniques and Interpretations","author":"Josephson","year":"2016"},{"key":"S1047951123003669_ref4","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1111\/jce.12081","article-title":"Potential new indication for ivabradine: treatment of a patient with congenital junctional ectopic tachycardia","volume":"24","author":"Al-Ghamdi","year":"2013","journal-title":"J Cardiovasc Electrophysiol"},{"key":"S1047951123003669_ref5","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.hrthm.2016.03.015","article-title":"Adjunctive ivabradine in combination with amiodarone: a novel therapy for pediatric congenital junctional ectopic tachycardia","volume":"13","author":"Dieks","year":"2016","journal-title":"Heart Rhythm"},{"key":"S1047951123003669_ref6","doi-asserted-by":"crossref","first-page":"226","DOI":"10.4103\/apc.APC_25_18","article-title":"Ivabradine for congenital junctional ectopic tachycardia in siblings","volume":"11","author":"Kothari","year":"2018","journal-title":"Ann Pediatr Cardiol"},{"key":"S1047951123003669_ref2","first-page":"157","volume-title":"Clinical Cardiac Electrophysiology in the Young","author":"Kean","year":"2016"},{"key":"S1047951123003669_ref7","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1111\/pace.13402","article-title":"Ivabradine is an effective antiarrhythmic therapy for congenital junctional ectopic tachycardia-induced cardiomyopathy during infancy: case studies","volume":"41","author":"Ergul","year":"2018","journal-title":"Pacing Clin Electrophysiol"},{"key":"S1047951123003669_ref1","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1016\/j.ijcard.2008.12.140","article-title":"A congenital form of junctional ectopic tachycardia","volume":"145","author":"Tulino","year":"2010","journal-title":"Int J Cardiol"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951123003669","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:09:36Z","timestamp":1708474176000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951123003669\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,18]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S1047951123003669"],"URL":"https:\/\/doi.org\/10.1017\/s1047951123003669","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,18]]},"assertion":[{"value":"\u00a9 The Author(s), 2023. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}