{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:32:03Z","timestamp":1790839923085,"version":"4.1.0"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123003839_as1\"><jats:title><jats:italic>Backgrounds<\/jats:italic> and Objectives:<\/jats:title><jats:p>The \u201cFast track\u201d protocol is an early extubation strategy to reduce ventilator-associated complications and induce early recovery after open-heart surgery. This study compared clinical outcomes between operating room extubation and ICU extubation after open-heart surgery in patients with CHD.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003839_as2\"><jats:title>Methods:<\/jats:title><jats:p>We retrospectively reviewed 215 patients who underwent open-heart surgery for CHDs under the scheduled \u201cFast track\u201d protocol between September 2016 and April 2022. The clinical endpoints were post-operative complications, including bleeding, respiratory and neurological complications, and hospital\/ICU stays.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003839_as3\"><jats:title>Results:<\/jats:title><jats:p>The patients were divided into operating room extubation (group O, n = 124) and ICU extubation (group I, n=91) groups. The most frequently performed procedures were patch closures of the atrial septal (107\/215, 49.8%) and ventricular septal (89\/215, 41.4%) defects. There were no significant differences in major post-operative complications or ICU and hospital stay duration between the two groups; however, patients in group I showed longer mechanical ventilatory support (0.0 min vs. 59.0 min (interquartile range: 17.0\u2013169.0), p &lt; 0.001). Patients in Group O showed higher initial lactate levels (3.2 \u00b1 1.7 mg\/dL versus 2.5 \u00b1 2.0 mg\/dL, p = 0.007) and more frequently used additional sedatives and opioid analgesics (33.1% versus 19.8%, p = 0.031).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123003839_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Extubation in the operating room was not beneficial for patients during post-operative ICU or hospital stay. Early extubation in the ICU resulted in more stable hemodynamics in the immediate post-operative period and required less use of sedatives and analgesics.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123003839","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T07:15:40Z","timestamp":1700464540000},"page":"914-918","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Extubation in operating room versus early extubation in ICU after open-heart surgery in patients with CHDs"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1725-5336","authenticated-orcid":false,"given":"Chan Hyeong","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9259-1391","authenticated-orcid":false,"given":"Jae Hong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4949-9688","authenticated-orcid":false,"given":"Hye Won","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sungkyu","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2837-7929","authenticated-orcid":false,"given":"Woong-Han","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6736-4464","authenticated-orcid":false,"given":"Sang-Hwan","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7511-4104","authenticated-orcid":false,"given":"Young-Eun","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3738-0081","authenticated-orcid":false,"given":"Jin-Tae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6375-1210","authenticated-orcid":false,"given":"Jae Gun","family":"Kwak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"S1047951123003839_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)61872-3"},{"key":"S1047951123003839_ref3","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2019.1153"},{"key":"S1047951123003839_ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-020-1051-3"},{"key":"S1047951123003839_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198510000-00010"},{"key":"S1047951123003839_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.03.013"},{"key":"S1047951123003839_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2010.01088.x"},{"key":"S1047951123003839_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2014.06.093"},{"key":"S1047951123003839_ref7","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2008.11.011"},{"key":"S1047951123003839_ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-018-1970-0"},{"key":"S1047951123003839_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951112002181"},{"key":"S1047951123003839_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)01306-5"},{"key":"S1047951123003839_ref17","doi-asserted-by":"publisher","DOI":"10.1177\/1089253213519291"},{"key":"S1047951123003839_ref18","doi-asserted-by":"publisher","DOI":"10.5090\/kjtcs.2018.51.4.247"},{"key":"S1047951123003839_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2018.10.153"},{"key":"S1047951123003839_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezw424"},{"key":"S1047951123003839_ref12","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000000789"},{"key":"S1047951123003839_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2008.00783.x"},{"key":"S1047951123003839_ref9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.064113"},{"key":"S1047951123003839_ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200204000-00011"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951123003839","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T11:31:10Z","timestamp":1713180670000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951123003839\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,20]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S1047951123003839"],"URL":"https:\/\/doi.org\/10.1017\/s1047951123003839","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,20]]},"assertion":[{"value":"\u00a9 The 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