{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T04:11:43Z","timestamp":1742616703076,"version":"3.40.2"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S104795112300402X_as1\"><jats:title>Background:<\/jats:title><jats:p>Haemodynamic changes in caval venous flow distribution occurring during bidirectional cavopulmonary anastomosis operation are still largely unknown.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112300402X_as2\"><jats:title>Methods:<\/jats:title><jats:p>Transit time flow measurements were performed in 15 cavopulmonary anastomosis operations. Superior and inferior caval vein flows were measured before and after the cavopulmonary anastomosis. Ratio of superior caval vein to overall caval veins flow was calculated.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112300402X_as3\"><jats:title>Results:<\/jats:title><jats:p>Mean superior caval vein flow ratio before cavopulmonary anastomosis was higher than previously reported for healthy children. Superior caval vein flow ratio decreased in 14\/15 patients after cavopulmonary anastomosis: mean 0.63 \u00b1 0.12 before versus 0.43 \u00b1 0.14 after. No linear correlation between intraoperative superior caval vein pressure and superior caval vein flow after cavopulmonary anastomosis was found. Neither Nakata index nor pulmonary vascular resistance measured at preoperative cardiac catheterisation correlated with intraoperative flows. None of patients died or required a take down.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112300402X_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>The higher mean superior caval vein flow ratio before cavopulmonary anastomosis compared to healthy children suggests flow redistribution in univentricular physiology to protect brain and neurodevelopment. The decrease of superior caval vein flow ratio after cavopulmonary anastomosis may reflect the flow redistribution related to trans-pulmonary gradient. The lack of correlation between superior caval vein pressure and superior caval vein flow could be explained by limited sample size and multifactorial determinants of caval veins flow, although pressure remain essential. Larger sample of measurements are needed to find flow range potentially predictive for clinical failure. To authors\u2019 knowledge, this is the first intraoperative flow measurement of both caval veins during cavopulmonary operations.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s104795112300402x","type":"journal-article","created":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T10:10:55Z","timestamp":1701425455000},"page":"1032-1038","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative transit-time flow measurement of caval veins before and after bidirectional cavopulmonary anastomosis"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6988-6183","authenticated-orcid":false,"given":"Sara C.","family":"Arrigoni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joost M. A. A.","family":"van der Maaten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc T. R.","family":"Roofthooft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland F.","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf M. F.","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tjark","family":"Ebels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2023,12,1]]},"reference":[{"volume-title":"Chapter 20.2 Blood Flow, Blood Pressure, and Resistance","year":"2019","author":"Biga","key":"S104795112300402X_ref17"},{"key":"S104795112300402X_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.31.2.172"},{"key":"S104795112300402X_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2018.01.037"},{"key":"S104795112300402X_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-005-0002-y"},{"key":"S104795112300402X_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951118000240"},{"key":"S104795112300402X_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2010.01.026"},{"key":"S104795112300402X_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.04.098"},{"key":"S104795112300402X_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.06.010"},{"key":"S104795112300402X_ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM195807172590304"},{"key":"S104795112300402X_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.05.043"},{"key":"S104795112300402X_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.05.087"},{"key":"S104795112300402X_ref13","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.7.1860"},{"key":"S104795112300402X_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)38300-X"},{"volume-title":"Circulation: The Veins","year":"1997","author":"Fung","key":"S104795112300402X_ref10"},{"key":"S104795112300402X_ref14","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14881"},{"key":"S104795112300402X_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.11.013"},{"key":"S104795112300402X_ref16","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951103000258"},{"key":"S104795112300402X_ref18","doi-asserted-by":"publisher","DOI":"10.5603\/KP.2013.0121"},{"key":"S104795112300402X_ref19","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezad077"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S104795112300402X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T11:09:35Z","timestamp":1742555375000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S104795112300402X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,1]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S104795112300402X"],"URL":"https:\/\/doi.org\/10.1017\/s104795112300402x","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2023,12,1]]},"assertion":[{"value":"\u00a9 The Author(s), 2023. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}