{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T20:35:11Z","timestamp":1770842111449,"version":"3.50.1"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951123004328_as1\"><jats:title>Background:<\/jats:title><jats:p>There are limited studies with medium-term follow-up following percutaneous pulmonary valve implantation and no studies with a gender-specific analysis.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123004328_as2\"><jats:title>Aims:<\/jats:title><jats:p>To report clinical outcomes up to five years following percutaneous pulmonary valve implantation using the two most common balloon expandable valves in a mixed population of paediatric and adult patients with an age and gender-specific analysis.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123004328_as3\"><jats:title>Methods:<\/jats:title><jats:p>This was a single-centre retrospective observation study. Relevant data were obtained retrospectively from the case files. Age and gender- specific analysis was performed using SPSS.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123004328_as4\"><jats:title>Results:<\/jats:title><jats:p>Totally, 58 patients (13 children, 45 adults) underwent percutaneous pulmonary valve implantation. Statistically significant reduction in median right ventricular outflow tract flow velocity following valve implantation was maintained for the whole five years in adults but not in children. There were no gender-specific differences despite the study being adequately powered. Independent of valve type used, there was significant reduction of the right ventricular outflow tract flow velocity in the immediate post valve implantation period (Edwards P = 0.001, Melody P = 0.013). There was a significant negative correlation between implanted valve Z-score and subsequent right ventricular outflow tract gradient during the first two years following valve implantation.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951123004328_as5\"><jats:title>Conclusion:<\/jats:title><jats:p>Gender does not significantly affect valve function following percutaneous pulmonary valve implantation. It is important to consider patients\u2019 age and body surface area in relation to existing right ventricular outflow tract size during decisions for percutaneous pulmonary valve implantation.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951123004328","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T01:57:31Z","timestamp":1704679051000},"page":"1267-1273","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Percutaneous pulmonary valve implantation in children and adults with an age and gender-specific analysis"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2455-9645","authenticated-orcid":false,"given":"Charalampos","family":"Kotidis","sequence":"first","affiliation":[{"name":"East Midlands Congenital Heart Centre, Glenfield 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}