{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T04:11:43Z","timestamp":1742616703139,"version":"3.40.2"},"reference-count":7,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Platypnea-orthodeoxia syndrome is characterised by hypoxemia and dyspnoea while upright that resolves when supine, typically associated with an interatrial communication. We present a case of platypnea-orthodeoxia syndrome associated with a sinus venosus atrial septal defect in a patient with multiple possible aetiologies of hypoxemia, including COVID-19 infection. Cardiac catheterisation with provocative maneuvers confirmed the diagnosis and symptoms resolved following defect closure. We suggest that in patients with platypnea-orthodeoxia syndrome, it is useful to obtain haemodynamic data while supine and upright<\/jats:p>","DOI":"10.1017\/s1047951124000416","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T07:35:56Z","timestamp":1709624156000},"page":"1139-1141","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Sinus venosus atrial septal defect presenting with platypnea-orthodeoxia syndrome in the setting of COVID-19 infection"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2101-8359","authenticated-orcid":false,"given":"Courtney H.","family":"Thomas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5865-9591","authenticated-orcid":false,"given":"Jeffrey D.","family":"Zampi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Joynt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,3,5]]},"reference":[{"key":"S1047951124000416_ref2","doi-asserted-by":"crossref","first-page":"141","DOI":"10.14797\/mdcj-14-2-141","article-title":"Treatment of platypnea-orthodeoxia syndrome in a patient with normal cardiac hemodynamics: a review of mechanisms with implications for management","volume":"14","author":"Porter","year":"2018","journal-title":"Methodist Debakey Cardiovasc J"},{"key":"S1047951124000416_ref1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/(SICI)1522-726X(199905)47:1<64::AID-CCD15>3.0.CO;2-6","article-title":"Platypnea-orthodeoxia syndrome: etiology, differential diagnosis, and management","volume":"47","author":"Cheng","year":"1999","journal-title":"Catheter Cardiovasc Interv"},{"key":"S1047951124000416_ref4","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.jcmg.2012.01.015","article-title":"Platypnea-orthodeoxia syndrome due to PFO and aortic dilation","volume":"5","author":"Shiraishi","year":"2012","journal-title":"JACC Cardiovasc Imaging"},{"key":"S1047951124000416_ref3","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s12928-014-0244-x","article-title":"Transcatheter closure of right-to-left atrial shunt in patients with platypnea-orthodeoxia syndrome associated with aortic elongation","volume":"29","author":"Takaya","year":"2014","journal-title":"Cardiovasc Interv Ther"},{"key":"S1047951124000416_ref5","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.echo.2006.09.008","article-title":"Anotomic interaction between the aortic root and the atrial septum: a prospective echocardiographic study","volume":"20","author":"Bertaux","year":"2007","journal-title":"J Am Soc Echocardiogr"},{"key":"S1047951124000416_ref7","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1513\/AnnalsATS.202011-1376CME","article-title":"The pathophysiology and dangers of silent hypoxemia in COVID-19 lung injury","volume":"18","author":"Swenson","year":"2021","journal-title":"Ann Am Thorac Soc"},{"key":"S1047951124000416_ref6","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1002\/ejhf.2058","article-title":"Haemodynamic characteristics of COVID-19 patients with acute respiratory distress syndrome requiring mechanical ventilation. An invasive assessment using right heart catheterization","volume":"22","author":"Caravita","year":"2020","journal-title":"Eur J Heart Fail"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951124000416","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T11:10:04Z","timestamp":1742555404000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951124000416\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,5]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S1047951124000416"],"URL":"https:\/\/doi.org\/10.1017\/s1047951124000416","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2024,3,5]]},"assertion":[{"value":"\u00a9 The Author(s), 2024. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}