{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T19:16:04Z","timestamp":1773342964607,"version":"3.50.1"},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T00:00:00Z","timestamp":1716768000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951124025204_as1\"><jats:title>Objectives:<\/jats:title><jats:p>The clinical data of patients with total anomalous pulmonary venous connection who underwent repair in our centre in the past 13 years were reviewed. In this study, we systemically reviewed our experience in the optimal surgical strategy for patients with total anomalous pulmonary venous connection, aiming to provide evidence for clinical decision-making.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124025204_as2\"><jats:title>Methods:<\/jats:title><jats:p>From January 1, 2009, to December 31, 2021, 122 patients undergoing surgical treatment for total anomalous pulmonary venous connection in our hospital were enrolled. Among them, 18 patients with single ventricle repair were excluded from the study. Multivariate analysis was used to determine the risk factors for early and late death and the risk factors for pulmonary vein obstruction.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124025204_as3\"><jats:title>Results:<\/jats:title><jats:p>There were 64 males and 40 females. The median age at surgery was 107 days (range, 25 days\u2013788 days), the median weight at surgery was 4.8 kg (range, 3 kg\u201322 kg), and the median follow-up was 59 months (range, 0\u2013150 months). Seven patients died early after surgery and six died late after discharge. Multivariable analysis indicated that prolonged cardiopulmonary bypass time was the only independent risk factor for early postoperative mortality. Multivariate analysis did not identify risk factors for late death. Emergency surgery, preoperative moderate and severe pulmonary hypertension, and prolonged cardiopulmonary bypass time were independent risk factors for postoperative pulmonary vein obstruction.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124025204_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Early and long-term late outcomes of repair in patients with total anomalous pulmonary venous connection have been encouraging. Postoperative pulmonary vein obstruction remains a major problem for specialists worldwide. Pulmonary vein obstruction should be considered in children with preoperative emergency surgery, moderate to severe pulmonary hypertension and prolonged cardiopulmonary bypass time, and regular follow-up is necessary.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951124025204","type":"journal-article","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T11:16:00Z","timestamp":1716808560000},"page":"1961-1970","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Long-term outcomes of repair in children with total anomalous pulmonary venous connection"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1256-3981","authenticated-orcid":false,"given":"Zhangwei","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoujun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,5,27]]},"reference":[{"key":"S1047951124025204_ref5","first-page":"74","article-title":"Efficacy and outcome of surgical treatment of 255 cases of total anomalous pulmonary venous connection: single center experience","volume":"36","author":"Zhangke","year":"2021","journal-title":"Chin Circ J"},{"key":"S1047951124025204_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.10.048"},{"key":"S1047951124025204_ref11","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2010.40.1.31"},{"key":"S1047951124025204_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.03.006"},{"key":"S1047951124025204_ref8","first-page":"10","article-title":"Early- and intermediate-term results of surgical correction in 328 patients with different drainage type of total anomalous pulmonary venous connection","volume":"33","author":"Ou","year":"2017","journal-title":"Chin J Thorac Cardiovasc Surg"},{"key":"S1047951124025204_ref16","first-page":"449","article-title":"Surgical repair for simple total anomalous pulmonary venous connection in neonates","volume":"37","author":"Ji","year":"2021","journal-title":"Chin J Thorac Cardiovasc Surg"},{"key":"S1047951124025204_ref17","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezt129"},{"key":"S1047951124025204_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivy267"},{"key":"S1047951124025204_ref18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.635441"},{"key":"S1047951124025204_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(98)00952-7"},{"key":"S1047951124025204_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)35231-6"},{"key":"S1047951124025204_ref14","first-page":"669","article-title":"Risk factor analysis for peri-operative mortality in patients with total anomalous pulmonary venous connection","volume":"32","author":"Jianfeng","year":"2017","journal-title":"Chin Circ J"},{"key":"S1047951124025204_ref20","first-page":"462","article-title":"Follow-up and further intervention for postoperative pulmonary obstruction of total anomalous pulmonary venous connection","volume":"37","author":"Qin","year":"2021","journal-title":"Chin J Thorac Cardiovasc Surg"},{"key":"S1047951124025204_ref13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.023889"},{"key":"S1047951124025204_ref4","first-page":"669","article-title":"Risk factors for postoperative pulmonary venous obstruction after correction of total anomalous pulmonary venous connection","volume":"37","author":"Mao","year":"2021","journal-title":"Chin J Thorac Cardiovasc Surg"},{"key":"S1047951124025204_ref1","first-page":"I12","article-title":"Surgical management of total anomalous pulmonary venous connection. Thirty-year trends","volume":"94","author":"Bando","year":"1996","journal-title":"Circulation"},{"key":"S1047951124025204_ref15","first-page":"95","article-title":"Clinical prognostic analysis of 135 patients after surgical correction of total anomalous pulmonary venous connection","volume":"14","author":"Yu","year":"2016","journal-title":"Chin J ECC"},{"key":"S1047951124025204_ref6","first-page":"581","volume-title":"Pediatric Cardiac Surgery","author":"Zhiwei","year":"2006"},{"key":"S1047951124025204_ref7","doi-asserted-by":"publisher","DOI":"10.1002\/9781118320754"},{"key":"S1047951124025204_ref12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.940825"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951124025204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T10:32:02Z","timestamp":1744108322000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951124025204\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,27]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S1047951124025204"],"URL":"https:\/\/doi.org\/10.1017\/s1047951124025204","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,27]]},"assertion":[{"value":"\u00a9 The Author(s), 2024. 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