{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:11:54Z","timestamp":1790187114658,"version":"4.1.0"},"reference-count":23,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951124025745_as1\"><jats:title>Objective:<\/jats:title><jats:p>To investigate functional outcomes in children who survived extracorporeal life support at 12 months follow-up post-discharge.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124025745_as2\"><jats:title>Background:<\/jats:title><jats:p>Some patients who require extracorporeal life support acquire significant morbidity during their hospitalisation. The Functional Status Scale is a validated tool that allows quantification of paediatric function.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124025745_as3\"><jats:title>Methods:<\/jats:title><jats:p>A retrospective study that included children placed on extracorporeal life support at a quaternary children\u2019s hospital between March 2020 and October 2021 and had follow-up encounter within 12 months post-discharge.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124025745_as4\"><jats:title>Results:<\/jats:title><jats:p>Forty-two patients met inclusion criteria: 33% female, 93% veno-arterial extracorporeal membrane oxygenation (VA ECMO), and 12% with single ventricle anatomy. Median age was 1.7 years (interquartile range 10 days\u201311.9 years). Median hospital stay was 51 days (interquartile range 34\u201391 days), and median extracorporeal life support duration was 94 hours (interquartile range 56\u2013142 hours). The median Functional Status Scale at discharge was 8.0 (interquartile range 6.3\u20138.8). The mean change in Functional Status Scale from discharge to follow-up at 9 months (n = 37) was \u22120.8 [95% confidence interval (CI) \u22121.3 to \u22120.4, <jats:italic>p<\/jats:italic> &lt; 0.001] and at 12 months (n = 34) was \u22121 (95% confidence interval \u22121.5 to \u22120.4, <jats:italic>p<\/jats:italic> &lt; 0.001); the most improvement was in the feeding score. New morbidity (Functional Status Scale increase of \u22653) occurred in 10 children (24%) from admission to discharge. Children with new morbidity were more likely to be younger (<jats:italic>p<\/jats:italic> = 0.01), have an underlying genetic syndrome (<jats:italic>p<\/jats:italic> = 0.02), and demonstrate evidence of neurologic injury by electroencephalogram or imaging (<jats:italic>p<\/jats:italic> = 0.05).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124025745_as5\"><jats:title>Conclusions:<\/jats:title><jats:p>In survivors of extracorporeal life support, the Functional Status Scale improved from discharge to 12-month follow-up, with the most improvement demonstrated in the feeding score.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951124025745","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T06:13:20Z","timestamp":1727676800000},"page":"2225-2230","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Paediatric survivors of extracorporeal life support functional outcomes at one-year 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