{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:20:50Z","timestamp":1773015650738,"version":"3.50.1"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T00:00:00Z","timestamp":1728864000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951124026350_as1\"><jats:title>Background:<\/jats:title><jats:p>The risk factors for reoperation and mortality after partial and intermediate atrioventricular canal defect repair are unclear. This study assessed the mid-term outcomes and risk factors for reoperation and mortality after partial and intermediate atrioventricular canal defect surgery.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124026350_as2\"><jats:title>Methods:<\/jats:title><jats:p>Ninety-seven patients who underwent primary repair of intermediate (n = 45) or partial (n = 52) atrioventricular canal defect between 2005 and 2019 were included in this single-centre study.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124026350_as3\"><jats:title>Results:<\/jats:title><jats:p>The median age was 5 years (2.7\u20138.9 years). The median follow-up time was 32 months (1.6\u201390.8 months). The estimated freedom from reoperation at 1, 5, and 10 years was 97%, 91%, and 73%, respectively.<\/jats:p><jats:p>In multivariable analyses, post-operative left atrioventricular valve regurgitation of grade II or higher (odds ratio [OR]: 5.3, 95% confidence interval [CI]: 1.8\u201315.5, <jats:italic>p<\/jats:italic> = 0.01) and post-operative residual intracardiac shunt (OR: 11.6, 95% CI: 1.6\u201385.8, <jats:italic>p<\/jats:italic> = 0.02) were risk factors for reoperation.<\/jats:p><jats:p>In multivariable analyses, perioperative reoperation (OR: 93.4, 95% CI: 3.9\u2013218.7, <jats:italic>p<\/jats:italic> = 0.01) and the need for right atrioventricular valve repair (OR: 11.2, 95% CI: 1.0 \u2013 123.3, <jats:italic>p<\/jats:italic> = 0.04) were risk factors for mortality. Mortality was higher in patients under 2.6 years of age.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124026350_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>For patients undergoing repair of partial or intermediate atrioventricular canal defect, those with post-operative left atrioventricular valve regurgitation of grade II or higher and post-operative residual intracardiac shunt have an increased reoperation risk. Higher mortality can be expected after a perioperative reoperation, and in patients requiring right atrioventricular valve repair during the index procedure.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951124026350","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T10:08:16Z","timestamp":1728900496000},"page":"2610-2618","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of mid-term outcomes of partial and intermediate atrioventricular canal defect surgery"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0345-453X","authenticated-orcid":false,"given":"Husnu F.","family":"Altin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5776-6993","authenticated-orcid":false,"given":"Oktay","family":"Korun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Cicek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Okan","family":"Yurdakok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5779-3249","authenticated-orcid":false,"given":"Yigit","family":"Kilic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9200-8242","authenticated-orcid":false,"given":"Arif","family":"Selcuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5333-4336","authenticated-orcid":false,"given":"Emine Hekim","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selma Oktay","family":"Ergin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Sasmazel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Numan A.","family":"Aydemir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,10,14]]},"reference":[{"key":"S1047951124026350_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.04.035"},{"key":"S1047951124026350_ref12","article-title":"Partial and intermediate atrioventricular septal defects without major associated cardiac anomalies","volume":"2015","author":"Sfyridis","year":"2015; 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