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Triheptanoin, a synthetic medium chain triglyceride, has been reported to reverse cardiomyopathy in some individuals, but there is limited literature in severe cases. We describe a neonatal onset of severe disease whose clinical course was not improved despite mechanical support and triheptanoin.<\/jats:p>","DOI":"10.1017\/s1047951124026386","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T06:49:56Z","timestamp":1736405396000},"page":"218-220","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Triheptanoin use for severe neonatal cardiomyopathy secondary to mitochondrial trifunctional protein deficiency: a first 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