{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T04:10:36Z","timestamp":1742616636682,"version":"3.40.2"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T00:00:00Z","timestamp":1733875200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951124036023_as1\"><jats:title>Introduction:<\/jats:title><jats:p>Alternate electrocardiogram acquisition with fewer leads lacks systematic evaluation in children. This study aims to determine if electrocardiograms with fewer leads maintain diagnostic accuracy in paediatrics.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124036023_as2\"><jats:title>Methods:<\/jats:title><jats:p>This is a single-centre review of 200 randomly selected standard 12-lead electrocardiograms from our hospital database (2017\u20132020) for patients aged 2 weeks to 21 years. An overlay technique generated 8-lead (limb + V1\/V6) and 6-lead (limb only) variations of the 12-lead tracings, resulting in a total of 600 electrocardiograms, which were then interpreted by two independent paediatric electrophysiologists.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124036023_as3\"><jats:title>Results:<\/jats:title><jats:p>In total, 18% (35\/200) of the baseline electrocardiograms were abnormal. Intervals were measured in lead II for all electrocardiograms. Comparing 12-lead to 6- and 8-lead electrocardiograms, there was almost perfect agreement for specific rhythm identification (97.5\u2013100%, \u03ba 0.85-1). The 8-lead showed substantial agreement with 12-lead electrocardiograms when identifying specific electrocardiogram patterns (97.5\u2013100%, \u03ba 0.66\u20131). A similar degree of agreement was not demonstrated with the 6-lead variant. Utilising the 12-lead electrocardiogram as the gold standard, sensitivity and specificity of the 8- and 6-lead electrocardiogram were &gt; 89% for specific rhythm identification. Specificity for specific pattern recognition was &gt; 99% while sensitivity was &lt; 90% for certain variables for both 6- and 8-lead electrocardiogram, likely due to smaller sample size and fewer abnormal electrocardiograms. There was high percent reader agreement (92.5\u2013100%).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951124036023_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>8-lead electrocardiograms provide comparable diagnostic accuracy to 12-lead electrocardiograms for children. This information holds potential for future technological advancements in electrocardiogram acquisition tailored specifically for paediatrics. Additional studies are required to further refine conventional electrocardiogram acquisition.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951124036023","type":"journal-article","created":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T03:49:18Z","timestamp":1733888958000},"page":"283-288","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating the diagnostic accuracy of reduced lead paediatric electrocardiograms"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5483-4359","authenticated-orcid":false,"given":"Megan Carroll","family":"Damera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Centanni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Sherman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Kline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher W.","family":"Follansbee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip M.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey E.","family":"Malloy-Walton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,12,11]]},"reference":[{"key":"S1047951124036023_ref7","first-page":"SC06","article-title":"Clinical profile of cardiac arrhythmias in children attending the out patient department of a tertiary paediatric care centre in chennai","volume":"10","author":"Premkumar","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"S1047951124036023_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02083144"},{"key":"S1047951124036023_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.118.005289"},{"key":"S1047951124036023_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2019.01.086"},{"key":"S1047951124036023_ref12","doi-asserted-by":"publisher","DOI":"10.1054\/jelc.2002.37150"},{"key":"S1047951124036023_ref3","first-page":"47","article-title":"The reconstruction of a 12-lead electrocardiogram from a reduced lead set using a focus time-delay neural network","volume":"37","author":"Smith","year":"2021","journal-title":"Acta Cardiol Sin"},{"key":"S1047951124036023_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2006.04.005"},{"key":"S1047951124036023_ref16","doi-asserted-by":"publisher","DOI":"10.1177\/11795476211069194"},{"key":"S1047951124036023_ref6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.019307"},{"key":"S1047951124036023_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-019-1223-8"},{"key":"S1047951124036023_ref15","doi-asserted-by":"publisher","DOI":"10.1109\/RBME.2013.2264282"},{"key":"S1047951124036023_ref5","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"S1047951124036023_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12683"},{"key":"S1047951124036023_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12138"},{"key":"S1047951124036023_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/ehjdh\/ztab083"},{"key":"S1047951124036023_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2020.10.005"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951124036023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T10:17:41Z","timestamp":1742552261000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951124036023\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,11]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S1047951124036023"],"URL":"https:\/\/doi.org\/10.1017\/s1047951124036023","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2024,12,11]]},"assertion":[{"value":"\u00a9 The Author(s), 2024. 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