{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T19:34:36Z","timestamp":1767987276992,"version":"3.49.0"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"unspecified","delay-in-days":33,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The incidence of Kawasaki Disease has a peak in the winter months with a trough in late summer\/early fall. Environmental\/exposure factors have been associated with a time-varying incidence. These factors were altered during the COVID-19 pandemic. The study was performed through the International Kawasaki Disease Registry. Data from patients diagnosed with acute Kawasaki Disease and Multiple Inflammatory Syndrome-Children were obtained. Guideline case definitions were used to confirm site diagnosis. Enrollment was from 1\/2020 to 7\/2023. The number of patients was plotted over time. The patients\/month were tabulated for the anticipated peak Kawasaki Disease season (December\u2013April) and non-peak season (May\u2013November). Data were available for 1975 patients from 11 large North American sites with verified complete data and uninterrupted site reporting. The diagnosis criteria were met for 531 Kawasaki Disease and 907 Multiple Inflammatory Syndrome-Children patients. For Multiple Inflammatory Syndrome-Children there were peaks in January of 2021 and 2022. For Kawasaki Disease, 2020 began (January\u2013March) with a seasonal peak (peak 26, mean 21) with a subsequent fall in the number of cases\/month (mean 11). After the onset of the pandemic (April 2020), there was no clear seasonal Kawasaki Disease variation (December\u2013April mean 12 cases\/month and May\u2013November mean 10 cases\/month). During the pandemic, the prevalence of Kawasaki Disease decreased and the usual seasonality was abolished. This may represent the impact of pandemic public health measures in altering environmental\/exposure aetiologic factors contributing to the incidence of Kawasaki Disease.<\/jats:p>","DOI":"10.1017\/s1047951124036047","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T05:50:02Z","timestamp":1733291402000},"page":"2329-2332","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Seasons of Kawasaki Disease during the COVID-19 pandemic"],"prefix":"10.1017","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9615-6138","authenticated-orcid":false,"given":"Todd T.","family":"Nowlen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2622-573X","authenticated-orcid":false,"given":"Ashraf S.","family":"Harahsheh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geetha","family":"Raghuveer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anji T.","family":"Yetman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7715-3169","authenticated-orcid":false,"given":"Nagib","family":"Dahdah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8168-3725","authenticated-orcid":false,"given":"Michael A.","family":"Portman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supriya S.","family":"Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6112-6860","authenticated-orcid":false,"given":"Michael","family":"Khoury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selemet","family":"Tierney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cedric","family":"Manlhiot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedrom","family":"Farid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian W.","family":"McCrindle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,12,4]]},"reference":[{"key":"S1047951124036047_ref24","doi-asserted-by":"publisher","DOI":"10.1002\/cbin.11997"},{"key":"S1047951124036047_ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191087"},{"key":"S1047951124036047_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2023.06.001"},{"key":"S1047951124036047_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000484"},{"key":"S1047951124036047_ref16","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-006460"},{"key":"S1047951124036047_ref2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074529"},{"key":"S1047951124036047_ref19","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.36863"},{"key":"S1047951124036047_ref20","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.17436"},{"key":"S1047951124036047_ref21","first-page":"3","article-title":"Changes in Kawasaki disease incidence and phenotype during the COVID-19 pandemic","volume":"70","author":"\u00dcnl\u00fc","year":"2023","journal-title":"Dan Med J"},{"key":"S1047951124036047_ref9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.054785"},{"key":"S1047951124036047_ref17","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2021.0099"},{"key":"S1047951124036047_ref14","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-051462"},{"key":"S1047951124036047_ref15","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12976"},{"key":"S1047951124036047_ref7","doi-asserted-by":"publisher","DOI":"10.3390\/children8080623"},{"key":"S1047951124036047_ref12","unstructured":"12. Anon. Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19). Centers for Disease Control and Prevention. 2020. Accessed December 16, 2023. https:\/\/emergency.cdc.gov\/han\/2020\/han002432.asp."},{"key":"S1047951124036047_ref18","unstructured":"18. Anon. Increased Respiratory Syncytial Virus (RSV) Activity in Parts of the Southeastern United States: New Prevention Tools Available to Protect Patients. Centers for Disease Control Health Alert Network. 2023. Accessed January 13, 2024. https:\/\/emergency.cdc.gov\/han\/2023\/han00498.asp."},{"key":"S1047951124036047_ref10","first-page":"1","article-title":"Changes in the clinical characteristics of Kawasaki disease after coronavirus disease (COVID-19) pandemic: a database analysis","volume":"37","author":"Kim","year":"2022","journal-title":"J Korean Med Sci"},{"key":"S1047951124036047_ref22","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE20210132"},{"key":"S1047951124036047_ref4","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2018.00374"},{"key":"S1047951124036047_ref3","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-93089-9"},{"key":"S1047951124036047_ref6","first-page":"1","article-title":"Kawasaki disease before and during the COVID-19 pandemic: a nationwide population-based study in the United States","volume":"XX","author":"Sakai-Bizmark","year":"2023","journal-title":"Pediatr Infect Dis J"},{"key":"S1047951124036047_ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2022.3756"},{"key":"S1047951124036047_ref13","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6937a6"},{"key":"S1047951124036047_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.138820"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951124036047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T07:04:42Z","timestamp":1739775882000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951124036047\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":24,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S1047951124036047"],"URL":"https:\/\/doi.org\/10.1017\/s1047951124036047","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"\u00a9 The Author(s), 2024. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}