{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T05:07:36Z","timestamp":1738732056816,"version":"3.37.0"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"unspecified","delay-in-days":7,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S104795112403659X_as1\"><jats:title>Background:<\/jats:title><jats:p>The Wolff\u2013Parkinson\u2013White pattern is a delta wave frequently detected in school-based cardiovascular screening programs in Japan. Although most children with Wolff\u2013Parkinson\u2013White pattern are asymptomatic, initial symptoms may include syncope or sudden death, necessitating accurate diagnosis and management. Delta waves can also indicate a fasciculoventricular pathway, which poses no risk and does not require management.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112403659X_as2\"><jats:title>Methods:<\/jats:title><jats:p>We reviewed the medical records of patients referred to our hospital between April 2008 and March 2022 to evaluate the electrocardiographic signs of the Wolff\u2013Parkinson\u2013White pattern. The existence of Wolff\u2013Parkinson\u2013White syndrome and fasciculoventricular pathway were determined based on atrioventricular block and QRS waveform changes after adenosine administration during sinus rhythm.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112403659X_as3\"><jats:title>Results:<\/jats:title><jats:p>The study cohort included 127 children (65 males; median age: 12.8 years, resting heart rate: 75 beats\/min, PR interval: 109 ms, and QRS duration: 101 ms). The adenosine administration test revealed a fasciculoventricular pathway, Wolff\u2013Parkinson\u2013White syndrome, and indeterminate findings in 64, 54, and 9 children, respectively. More than 60% of children with a QRS duration \u2264 120 ms had a fasciculoventricular pathway. Age \u2264 12 years, QRS duration &gt;120 ms, and type A category (children with R\/S ratios &gt;1 in lead V1) were identified as independent risk factors for Wolff\u2013Parkinson\u2013White syndrome. No adverse events were observed in any child.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112403659X_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>The adenosine administration test is safe and feasible for differentiating Wolff\u2013Parkinson\u2013White syndrome from fasciculoventricular pathways and can reduce the unnecessary management of children with fasciculoventricular pathways.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s104795112403659x","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T05:51:36Z","timestamp":1736315496000},"page":"46-52","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy and safety of the adenosine administration test in the management of Wolff\u2013Parkinson\u2013White pattern in children with delta waves"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4091-9068","authenticated-orcid":false,"given":"Kentaro","family":"Kogawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reiji","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daishi","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Hoshino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"S104795112403659X_ref7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.03206.x"},{"key":"S104795112403659X_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.1985.tb00655.x"},{"key":"S104795112403659X_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.02.011"},{"key":"S104795112403659X_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.11.018"},{"key":"S104795112403659X_ref2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw072"},{"key":"S104795112403659X_ref3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.055350"},{"key":"S104795112403659X_ref11","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-66-0153"},{"key":"S104795112403659X_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.12.006"},{"key":"S104795112403659X_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.02.009"},{"key":"S104795112403659X_ref4","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.019703"},{"key":"S104795112403659X_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12913"},{"key":"S104795112403659X_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13935"},{"key":"S104795112403659X_ref1","first-page":"e471","article-title":"2015 ACC\/AHA\/HRS guideline for the management of adult patients with supraventricular tachycardia: executive summary: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","volume":"133","author":"Page","year":"2016","journal-title":"Circulation"},{"key":"S104795112403659X_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.10.009"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S104795112403659X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T05:10:32Z","timestamp":1738645832000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S104795112403659X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S104795112403659X"],"URL":"https:\/\/doi.org\/10.1017\/s104795112403659x","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}