{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T05:00:14Z","timestamp":1769749214066,"version":"3.49.0"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S104795112500006X_as1\"><jats:title>Background:<\/jats:title><jats:p>Despite patent ductus arteriosus closure in premature infants is a relatively fast procedure, it involves specific steps for equipment exchange and the use of a 4-Fr catheter, which may be large for tiny infants, potentially causing haemodynamic instability or tricuspid valve regurgitation.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112500006X_as2\"><jats:title>Objectives:<\/jats:title><jats:p>This study aims to describe the early experience with a new technique designed to simplify transcatheter patent ductus arteriosus closure in premature infants. It enables the closure using the KA micro plug device via a single microcatheter without equipment exchanges and contrast exposure. This technique involves a simple modification of the microcatheter by creating a curved tip.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112500006X_as3\"><jats:title>Methods:<\/jats:title><jats:p>This is a retrospective, single-institution study involving premature infants who underwent attempted transcatheter patent ductus arteriosus closure using a manually modified microcatheter of the KA micro plug device at Stead Family Children\u2019s Hospital.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112500006X_as4\"><jats:title>Results:<\/jats:title><jats:p>Five patients underwent transcatheter patent ductus arteriosus closure using a KA micro plug with a modified microcatheter. The procedure was successful in all patients, with no haemodynamic instability. The median (range) for procedural weight, time, and radiation dose were 1055 g (730\u20131330), 12 minutes (11\u201319), and 0.49 \u00b5Gy.m<jats:sup>2<\/jats:sup> (0.14\u20131), respectively. At a median follow-up of 1.1 months (0.17\u20132.6), all patients maintained good device position without residual shunt or other concerning echocardiogram findings.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112500006X_as5\"><jats:title>Conclusions:<\/jats:title><jats:p>Transcatheter patent ductus arteriosus closure in infants weighing less than 1500 g can be successfully performed using a KA micro plug device through a microcatheter with zero-contrast use, low radiation exposure, and a short procedure time.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s104795112500006x","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T10:04:37Z","timestamp":1738231477000},"page":"554-559","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Patent ductus arteriosus closure in infants weighing less than 1500 g via a tiny microcatheter: a simple technique with zero-contrast exposure"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0811-446X","authenticated-orcid":false,"given":"Bassel","family":"Mohammad Nijres","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Panicucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"key":"S104795112500006X_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29298"},{"key":"S104795112500006X_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26878"},{"key":"S104795112500006X_ref4","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28973"},{"key":"S104795112500006X_ref14","first-page":"355","article-title":"Patent ductus arteriosus occlusion in premature infants","volume":"13","author":"Parkerson","year":"2024","journal-title":"Interv Cardiol Clin"},{"key":"S104795112500006X_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2024.101211"},{"key":"S104795112500006X_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-022-02903-2"},{"key":"S104795112500006X_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.31046"},{"key":"S104795112500006X_ref7","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.025343"},{"key":"S104795112500006X_ref12","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12725"},{"key":"S104795112500006X_ref1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2418"},{"key":"S104795112500006X_ref2","first-page":"184","article-title":"Patent ductus arteriosus, indomethacin and necrotizing enterocolitis in very low birth weight infants: a population-based study","volume":"40","author":"Dollberg","year":"2005","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"S104795112500006X_ref17","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.121.010600"},{"key":"S104795112500006X_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2021.06.005"},{"key":"S104795112500006X_ref3","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202203-0570OC"},{"key":"S104795112500006X_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-024-03620-8"},{"key":"S104795112500006X_ref5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.123.013723"},{"key":"S104795112500006X_ref8","first-page":"1","article-title":"Patent ductus arteriosus closure in small infants weighing less than 1500 g using KA micro plug: steps and tips","volume":"34","author":"Mohammad Nijres","year":"2024","journal-title":"Cardiol Young"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S104795112500006X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T12:05:27Z","timestamp":1743509127000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S104795112500006X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,30]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S104795112500006X"],"URL":"https:\/\/doi.org\/10.1017\/s104795112500006x","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,30]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. 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