{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:06:04Z","timestamp":1790805964593,"version":"4.1.0"},"reference-count":46,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951125000150_as1\"><jats:title>Objective:<\/jats:title><jats:p>The most common cause of morbidity and mortality in type 1 diabetes mellitus is cardiovascular system involvement. Sudden death has been reported in type 1 diabetes mellitus patients. To analyse the use of the cardiac electrophysiological balance index in predicting ventricular arrhythmias in children with type 1 diabetes mellitus disease.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125000150_as2\"><jats:title>Methods:<\/jats:title><jats:p>One hundred type 1 diabetes mellitus paediatric patients and 100 healthy children, divided into three groups according to their haemoglobin A1C levels, were included in the study. All participants were evaluated with transthoracic echocardiography, 12-lead electrocardiography, and 24-h Holter after a detailed physical examination. Systolic and diastolic function parameters, electrocardiography intervals, and heart rate variability parameters were evaluated.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125000150_as3\"><jats:title>Results:<\/jats:title><jats:p>The mean age in the type 1 diabetes mellitus and control groups was 11.52 (\u00b1 3.52) and 11.78 (\u00b1 3.45) years, respectively. In total, 57% of the type 1 diabetes mellitus group and 56% of the control group were male. The mean haemoglobin A1C value was 9.14% (\u00b1 1.79) and the disease duration was 3.71 years (\u00b1 3.13). The type 1 diabetes mellitus group had a higher QTc duration, deceleration time duration, A velocity, and a lower E\/A ratio than the control group. In the type 1 diabetes mellitus group, Tpe, Tpe\/QT ratio, QTc\/QRS ratio, Tpe\/QRS ratio, Tpe\/(QT \u00d7 QRS) ratio values were significantly higher than in the control group.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125000150_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Children with type 1 diabetes mellitus are at risk for atrial and ventricular arrhythmias without valvular disease, ischemic heart disease, or diastolic dysfunction despite normal systolic function. No correlation was found between disease duration, metabolic control, autonomic function parameters, and arrhythmia risk; however, it was associated with diastolic function parameters.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951125000150","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T07:39:50Z","timestamp":1739345990000},"page":"593-599","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of cardiac electrophysiological balance index in children diagnosed with type 1 diabetes mellitus"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3784-7849","authenticated-orcid":false,"given":"Kerem","family":"Erta\u015f","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4415-4437","authenticated-orcid":false,"given":"\u00d6zlem","family":"G\u00fcl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruken","family":"Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eervan","family":"\u00d6zalkak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"S1047951125000150_ref20","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.191096"},{"key":"S1047951125000150_ref44","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199805)15:5<402::AID-DIA594>3.0.CO;2-1"},{"key":"S1047951125000150_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2008.07.030"},{"key":"S1047951125000150_ref31","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(98)00091-6"},{"key":"S1047951125000150_ref12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.25.3075"},{"key":"S1047951125000150_ref33","first-page":"275","article-title":"Evaluation of electrocardiographic ventricular depolarization and repolarization variables in Type 1 diabetes mellitus","volume":"114","author":"Inan\u0131r","year":"2020","journal-title":"Arq Bras Cardiol"},{"key":"S1047951125000150_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(89)80014-8"},{"key":"S1047951125000150_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.10.005"},{"key":"S1047951125000150_ref26","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2848759"},{"key":"S1047951125000150_ref28","doi-asserted-by":"publisher","DOI":"10.1177\/107424849700200108"},{"key":"S1047951125000150_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-53480-4.00006-0"},{"key":"S1047951125000150_ref46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2011.00762.x"},{"key":"S1047951125000150_ref37","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.25.4.702"},{"key":"S1047951125000150_ref24","doi-asserted-by":"publisher","DOI":"10.1210\/er.2003-0012"},{"key":"S1047951125000150_ref32","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(01)00443-0"},{"key":"S1047951125000150_ref42","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-018-3122-1"},{"key":"S1047951125000150_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2001.tb00101.x"},{"key":"S1047951125000150_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.vascn.2013.01.003"},{"key":"S1047951125000150_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2018.06.004"},{"key":"S1047951125000150_ref40","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)80028-F"},{"key":"S1047951125000150_ref45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2004.02.002"},{"key":"S1047951125000150_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.05.021"},{"key":"S1047951125000150_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2009.00582.x"},{"key":"S1047951125000150_ref43","first-page":"732","article-title":"Diabetic cardiomyopathy","volume":"11","author":"Acar","year":"2011","journal-title":"Anadolu Kardiyol Derg"},{"key":"S1047951125000150_ref1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.29.11.374"},{"key":"S1047951125000150_ref27","doi-asserted-by":"publisher","DOI":"10.1017\/S104795110999031X"},{"key":"S1047951125000150_ref25","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2001.281.4.H1800"},{"key":"S1047951125000150_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(99)00140-0"},{"key":"S1047951125000150_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew082"},{"key":"S1047951125000150_ref18","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/europace\/euw210","article-title":"(Tpeak - 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