{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T04:10:54Z","timestamp":1742616654770,"version":"3.40.2"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T00:00:00Z","timestamp":1738022400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951125000228_as1\"><jats:title>Aims:<\/jats:title><jats:p>To evaluate the prevalence, long-term mortality, and clinical characteristics in total cavopulmonary connection patients with excellent functional outcomes.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125000228_as2\"><jats:title>Methods and results:<\/jats:title><jats:p>A retrospective study of cardiopulmonary exercise test results in 288 patients after total cavopulmonary connection from a single-centre nationwide database. A subgroup of 88 (30.6%) patients (45 women; 51.1%), at a median age 13.0 [interquartile range 11.0; 18.0] years achieved \u226580% of predicted VO2peak value (Super-Fontan phenotype). Survival free from death or heart transplantation 20 years after surgery was 100.0% in the Super-Fontan group versus 94.0% in the rest of the cohort (<jats:italic>p<\/jats:italic> = 0.04). Super-Fontan patients were younger, had lower body mass index, lower regurgitant fraction on atrioventricular valve, and larger preoperative McGoon ratio than the rest of the cohort (<jats:italic>p<\/jats:italic> = 0.002, <jats:italic>p<\/jats:italic> &lt; 0.0001, <jats:italic>p<\/jats:italic> = 0.004, and <jats:italic>p<\/jats:italic> = 0.04, respectively). Females and tricuspid atresia patients were significantly more prevalent in the Super-Fontan group than in the rest of the cohort (<jats:italic>p<\/jats:italic> = 0.02 for both). There was no difference regarding systemic ventricle morphology, fenestration presence, or ejection fraction of systemic ventricle between the Super-Fontan group and the rest of the total cavopulmonary connection cohort (<jats:italic>p<\/jats:italic> = 0.06, <jats:italic>p<\/jats:italic> = 0.09, and <jats:italic>p<\/jats:italic> = 0.64, respectively).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125000228_as3\"><jats:title>Conclusions:<\/jats:title><jats:p>The subgroup of Super-Fontan patients has unique clinical characteristics when compared to the rest of the total cavopulmonary connection nationwide cohort. Besides superior VO2peak results, Super-Fontan patients tend to have lower long-term mortality, body mass index, and atrioventricular valve, greater preoperative pulmonary dimensions, and a higher prevalence of females and tricuspid atresia patients. There was no variance in morphology of the systemic ventricle, or presence of fenestration.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951125000228","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T06:30:33Z","timestamp":1738045833000},"page":"413-417","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence, predictors, and mortality of Super-Fontan patients in a single-centre nationwide cohort"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2386-0444","authenticated-orcid":false,"given":"Vojt\u011bch","family":"Illinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kry\u0161tof","family":"Slab\u00fd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u0159\u00ed","family":"Radvansk\u00fd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denisa","family":"Ji\u010d\u00ednsk\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3528-3202","authenticated-orcid":false,"given":"Ond\u0159ej","family":"Materna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,1,28]]},"reference":[{"key":"S1047951125000228_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2020.03.022"},{"key":"S1047951125000228_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.13747"},{"key":"S1047951125000228_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.12.046"},{"key":"S1047951125000228_ref14","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.117.004575"},{"first-page":"288","year":"1988","author":"M\u00e1\u010dek","key":"S1047951125000228_ref3"},{"key":"S1047951125000228_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/21501351221087695"},{"key":"S1047951125000228_ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951121003516"},{"key":"S1047951125000228_ref1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.764273"},{"key":"S1047951125000228_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131166"},{"key":"S1047951125000228_ref4","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.016850"},{"key":"S1047951125000228_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2023.05.010"},{"key":"S1047951125000228_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12222"},{"key":"S1047951125000228_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.10.047"},{"key":"S1047951125000228_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2019.11.006"},{"key":"S1047951125000228_ref10","first-page":"1","article-title":"Exercise capacity and predictors of performance after fontan: results from the pediatric heart network Fontan 3 Study","volume":"25","author":"Goldberg","year":"2020","journal-title":"Pediatr Cardiol"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951125000228","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T10:17:14Z","timestamp":1742552234000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951125000228\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,28]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S1047951125000228"],"URL":"https:\/\/doi.org\/10.1017\/s1047951125000228","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2025,1,28]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. 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