{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:37:07Z","timestamp":1789425427353,"version":"build-2803163510"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,5]]},"abstract":"Abstract<\/jats:title>\n \n Objective:<\/jats:title>\n We explore the role of targeted echocardiography as a screening tool for bicuspid aortic valve and left ventricular hypertrophy, specifically assessing the risk of missing significant cardiac findings that would otherwise be identified by comprehensive echocardiograms.<\/jats:p>\n <\/jats:sec>\n \n Method:<\/jats:title>\n Children < 18 years at initial echocardiogram for indications of \u201cfamily history of bicuspid aortic valve\u201d and \u201cleft ventricular hypertrophy on electrocardiogram\u201d were queried. Cardiology clinic notes and complete echocardiogram reports were reviewed for additional background histories and incidental findings. Follow-up clinic visits, if any, and management for those with incidental findings were reviewed.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Bicuspid aortic valve group included 138 patients, 71 (51%) males and mean age at comprehensive echo was 8.4 \u00b1 4.8 years. Bicuspid aortic valve was found in 3.6%, incidental findings were found in 15 (11%), and follow-up was recommended in 4 (2.8%). Left ventricular hypertrophy group included 70 patients, 58 (83%) males and mean age at echo 10.9 \u00b1 4.7 years. Left ventricular hypertrophy was found in 2.8%, incidental findings were found in 9 (13%), and follow-up was recommended in 2 (2.8%).<\/jats:p>\n None of the follow-up group developed symptoms or required cardiac medications, exercise restrictions, or catheter or surgical-based interventions, except for one case of mild aortic root dilation who was restricted from heavy weightlifting.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The risk of missing clinically important findings with targeted echocardiography that would have been identified with comprehensive echocardiography is extremely low for screening indications of isolated left ventricular hypertrophy on electrocardiogram or family history of bicuspid aortic valve, suggesting that targeted echocardiography could be an effective screening tool.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/s1047951125001490","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T02:37:11Z","timestamp":1745203031000},"page":"921-925","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Potential role of targeted echocardiography as a screening test for select diagnoses in the paediatric population: bicuspid aortic valve and left ventricular hypertrophy"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0227-1528","authenticated-orcid":false,"given":"Christina","family":"Yang","sequence":"first","affiliation":[{"name":"University of Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay A.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret M.","family":"Vernon","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Conwell","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujatha","family":"Buddhe","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,4,21]]},"reference":[{"key":"S1047951125001490_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.13325"},{"key":"S1047951125001490_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000002271"},{"key":"S1047951125001490_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.08.003"},{"key":"S1047951125001490_ref4","first-page":"48","article-title":"Reliability of transthoracic echocardiography in the assessment of aortic valve morphology: pathological correlation in 178 patients","volume":"15","author":"Chan","year":"1999","journal-title":"Can J Cardiol"},{"key":"S1047951125001490_ref3","doi-asserted-by":"publisher","DOI":"10.1111\/echo.14167"},{"key":"S1047951125001490_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.05.030"},{"key":"S1047951125001490_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ehjqcco\/qcab047"},{"key":"S1047951125001490_ref8","doi-asserted-by":"publisher","DOI":"10.23937\/2377-4630\/2\/1\/1023"},{"key":"S1047951125001490_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.740878"},{"key":"S1047951125001490_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-021-04153-5"},{"key":"S1047951125001490_ref1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.83.1.81"},{"key":"S1047951125001490_ref16","unstructured":"16. Insurance and cost of care. Seattle Children\u2019s Hospital. Accessed December 28. 2024. http:\/\/www.seattlechildrens.org\/clinics\/paying-for-care\/insurance."},{"key":"S1047951125001490_ref12","doi-asserted-by":"publisher","DOI":"10.3390\/jimaging9020050"},{"key":"S1047951125001490_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2023.11.015"},{"key":"S1047951125001490_ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-016-0205-7"},{"key":"S1047951125001490_ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-018-1907-7"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951125001490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T10:29:41Z","timestamp":1775903381000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951125001490\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,21]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["S1047951125001490"],"URL":"https:\/\/doi.org\/10.1017\/s1047951125001490","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,21]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}