{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T11:00:38Z","timestamp":1775905238492,"version":"3.50.1"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T00:00:00Z","timestamp":1744588800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951125001568_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aimed to evaluate the association between serum magnesium levels and the risk of symptomatic patent ductus arteriosus in premature infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125001568_as2\">\n                    <jats:title>Material and Method:<\/jats:title>\n                    <jats:p>This retrospective single-centre cohort study analysed the medical records of patients. Neonates were categorised into two groups based on the presence or absence of symptomatic patent ductus arteriosus. Demographic factors including gender, gestational age, type of birth, birth weight, multiple pregnancies, medical treatment for duct closure or surgical ligation, length of hospital stay, and mortality and neonatal outcomes were compared between the groups. The relationship between serum magnesium levels at 24 hours of age and the risk of symptomatic patent ductus arteriosus and other neonatal morbidities was assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125001568_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      This study found no significant relationship between symptomatic patent ductus arteriosus and serum magnesium levels. Additionally, no significant differences were observed between serum magnesium levels and ductal diameter, nor in the need for medical or surgical intervention for symptomatic patent ductus arteriosus. However, neonates with serum magnesium levels greater than 3 mg\/dL exhibited a significantly higher incidence of respiratory distress syndrome. Conversely, the prevalence of bronchopulmonary dysplasia was significantly lower in this group, with both findings reaching statistical significance (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125001568_as4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>These results suggest that while serum magnesium levels may not be a reliable marker for symptomatic patent ductus arteriosus, they could have clinical implications in the modulation of neonatal respiratory outcomes. Further research is warranted to explore the underlying mechanisms and assess the potential therapeutic role of magnesium in the management of neonatal morbidities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951125001568","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T08:46:04Z","timestamp":1744620364000},"page":"903-907","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of the relationship between serum magnesium levels, patent ductus arteriosus, and other neonatal morbidities: a retrospective observational study"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7858-7292","authenticated-orcid":false,"given":"Selma","family":"Aktas","sequence":"first","affiliation":[{"name":"Acibadem Mehmet Ali Aydinlar University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eda","family":"Albayrak","sequence":"additional","affiliation":[{"name":"Acibadem Atakent Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6590-6055","authenticated-orcid":false,"given":"Osman","family":"Guvenc","sequence":"additional","affiliation":[{"name":"Acibadem Atakent Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebru","family":"Kazanci","sequence":"additional","affiliation":[{"name":"Acibadem Maslak Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysegul","family":"Inamlik","sequence":"additional","affiliation":[{"name":"Acibadem Mehmet Ali Aydinlar University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayse Pelin","family":"Ozcan","sequence":"additional","affiliation":[{"name":"Acibadem Mehmet Ali Aydinlar University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayse","family":"Korkmaz","sequence":"additional","affiliation":[{"name":"Mehmet Ali Ayd\u0131nlar University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serdar","family":"Beken","sequence":"additional","affiliation":[{"name":"Mehmet Ali Ayd\u0131nlar University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,4,14]]},"reference":[{"key":"S1047951125001568_ref4","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2010.62"},{"key":"S1047951125001568_ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-1209"},{"key":"S1047951125001568_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1997.tb15185.x"},{"key":"S1047951125001568_ref7","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-197704000-00276"},{"key":"S1047951125001568_ref17","first-page":"101","article-title":"Pulmonary response to hyperoxia: effects 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