{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T12:59:34Z","timestamp":1781182774499,"version":"3.54.1"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"unspecified","delay-in-days":43,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,6]]},"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n The Takeuchi procedure remains an important surgical option for treating anomalous origin of the left coronary artery from the pulmonary artery, particularly in cases where direct coronary reimplantation is not feasible. However, long-term outcome data in paediatric patients are limited.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n We retrospectively reviewed 18 paediatric patients who underwent Takeuchi repair between 2007 and 2023. Clinical characteristics, echocardiographic data, and outcomes\u2014including survival, ventricular function, mitral regurgitation, and reintervention\u2014were analysed. Kaplan\u2013Meier analysis was used to assess survival and freedom from reintervention, and paired comparisons were evaluated using the Wilcoxon signed-rank test.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The median age at surgery was 6 months (range: 25 days to 12 years). Preoperative left ventricular ejection fraction was significantly depressed (median 23.5%), and mitral regurgitation was present in all patients. There were two early deaths (11.1%), both in patients with severe heart failure. No late mortality was observed during a maximum follow-up of 10.9\u00a0years. All survivors achieved New York Heart Association class I status. Left ventricular ejection fraction improved significantly postoperatively (\n p<\/jats:italic>\n < 0.0001), and mitral regurgitation grade also decreased significantly (\n p<\/jats:italic>\n < 0.001), with 94.4% showing only mild residual mitral regurgitation. Reintervention occurred in three patients (16.7%) for pulmonary artery stenosis or baffle leak. Freedom from reintervention at 10.9 years was 66.7%.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The Takeuchi procedure offers excellent survival and functional recovery in paediatric anomalous origin of the left coronary artery from the pulmonary artery patients when coronary translocation is not feasible. Although late complications such as pulmonary artery stenosis or baffle leak can occur, outcomes remain favourable with appropriate follow-up.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/s1047951125100528","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T08:38:52Z","timestamp":1752482332000},"page":"1205-1210","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Takeuchi repair for anomalous origin of the left coronary artery from the pulmonary artery: functional recovery and late complications in an 18-patient cohort"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6495-1639","authenticated-orcid":false,"given":"Osman Nuri","family":"Tuncer","sequence":"first","affiliation":[{"name":"Ege University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahsati","family":"Akhundova","sequence":"additional","affiliation":[{"name":"Ege University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ert\u00fcrk","family":"Levent","sequence":"additional","affiliation":[{"name":"Ege University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y\u00fcksel","family":"Atay","sequence":"additional","affiliation":[{"name":"Ege University Faculty of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"S1047951125100528_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2021.07.053"},{"key":"S1047951125100528_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.08.221"},{"key":"S1047951125100528_ref16","first-page":"308","article-title":"Long-term results after repair of anomalous origin of left coronary artery from the pulmonary artery: Takeuchi repair versus coronary transfer","volume":"51","author":"Neumann","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"key":"S1047951125100528_ref14","doi-asserted-by":"publisher","DOI":"10.33963\/KP.14816"},{"key":"S1047951125100528_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.hjc.2023.02.003"},{"key":"S1047951125100528_ref1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.292085059"},{"key":"S1047951125100528_ref3","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-12-1321"},{"key":"S1047951125100528_ref2","article-title":"Present, and future of surgical treatment of anomalous left coronary artery from the pulmonary artery","author":"Past","year":"2024","journal-title":"Pediatr Cardiol"},{"key":"S1047951125100528_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.05.051"},{"key":"S1047951125100528_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2019.04.018"},{"key":"S1047951125100528_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2020.06.130"},{"key":"S1047951125100528_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytab074"},{"key":"S1047951125100528_ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0260-5"},{"key":"S1047951125100528_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2021.02.035"},{"key":"S1047951125100528_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.15247"},{"key":"S1047951125100528_ref7","doi-asserted-by":"publisher","DOI":"10.21470\/1678-9741-2018-0376"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951125100528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T12:16:53Z","timestamp":1781180213000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951125100528\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S1047951125100528"],"URL":"https:\/\/doi.org\/10.1017\/s1047951125100528","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}