{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T05:33:51Z","timestamp":1769319231252,"version":"3.49.0"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T00:00:00Z","timestamp":1757030400000},"content-version":"unspecified","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951125100565_as1\"><jats:title>Objective:<\/jats:title><jats:p>Chronic pulmonary regurgitation following tetralogy of Fallot repair burdens the right ventricle. This study evaluated early outcomes of pulmonary valve reconstruction using right atrial tissue versus standard transannular patch repair.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100565_as2\"><jats:title>Methods:<\/jats:title><jats:p>A retrospective analysis of 412 tetralogy of Fallot patients (2014\u20132024) was conducted: Atrial Valve Group (<jats:italic>n<\/jats:italic> = 205) underwent valve reconstruction; No-Valve\u00a0Group (<jats:italic>n<\/jats:italic> = 207) received standard repair. Patients were followed for 1 year with echocardiographic assessments. Outcomes included right ventricular insufficiency, ventilation duration, and ICU stay.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100565_as3\"><jats:title>Results:<\/jats:title><jats:p>Atrial Valve Group had lower right ventricular insufficiency at 12 months (9.3% vs. 19.8%, <jats:italic>p<\/jats:italic> = 0.004, OR = 2.39, 95% CI: 1.32\u20134.33), shorter ventilation times (6.1 vs. 18.0 hours, <jats:italic>p<\/jats:italic> &lt; 0.001, Cohen\u2019s <jats:italic>d<\/jats:italic> = 3.54), and reduced ICU stays (3.0 vs. 5.7 days, <jats:italic>p<\/jats:italic> &lt; 0.001, Cohen\u2019s <jats:italic>d<\/jats:italic> = 1.87), despite longer CPB durations (47.1 vs. 40.5 minutes, <jats:italic>p<\/jats:italic> = 0.02).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100565_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Right atrial tissue reconstruction reduces early and intermediate-term right ventricular dysfunction post-tetralogy of Fallot repair. Long-term studies are needed.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951125100565","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T08:40:29Z","timestamp":1757061629000},"page":"1824-1843","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Early results of complete surgical correction of tetralogy of Fallot with pulmonary valve formation from the right atrium: a comparative analysis with traditional correction without valve construction"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4680-785X","authenticated-orcid":false,"given":"Mustafa Kemal","family":"Av\u015far","sequence":"first","affiliation":[{"name":"\u00c7ukurova University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5706-2363","authenticated-orcid":false,"given":"Ramush","family":"Bejiqi","sequence":"additional","affiliation":[{"name":"University of Gjakova, Gjakova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2555-2800","authenticated-orcid":false,"given":"Yasin","family":"G\u00fczel","sequence":"additional","affiliation":[{"name":"\u00c7ukurova University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3011-8152","authenticated-orcid":false,"given":"Cenap","family":"Zeybek","sequence":"additional","affiliation":[{"name":"Medicana International Istanbul Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6323-8495","authenticated-orcid":false,"given":"Bar\u0131s","family":"Kirat","sequence":"additional","affiliation":[{"name":"Medipol Mega Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8117-4779","authenticated-orcid":false,"given":"\u0130brahim Ozgur","family":"Onsel","sequence":"additional","affiliation":[{"name":"Medicana International Istanbul Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9405-8179","authenticated-orcid":false,"given":"Mehmet Salih","family":"Bilal","sequence":"additional","affiliation":[{"name":"Medicana Ata\u015fehir Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,9,5]]},"reference":[{"key":"S1047951125100565_ref14","first-page":"202","article-title":"Late failure of polytetrafluoroethylene valves in right ventricular outflow tract reconstruction","volume":"115","author":"Kumar","year":"2023","journal-title":"Ann Thorac Surg"},{"key":"S1047951125100565_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60657-7"},{"key":"S1047951125100565_ref12","first-page":"1961","article-title":"Pulmonary regurgitation after tetralogy of fallot repair: a tolerable nuisance or a time bomb?","volume":"142","author":"Tweddell","year":"2020","journal-title":"Circulation"},{"key":"S1047951125100565_ref16","first-page":"843","article-title":"Long-term results of monocuspid valves for right ventricular outflow tract reconstruction","volume":"107","author":"Tanase","year":"2019","journal-title":"Ann Thorac Surg"},{"key":"S1047951125100565_ref4","first-page":"2310","article-title":"Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of fallot","volume":"117","author":"Valente","year":"2008","journal-title":"Circulation"},{"key":"S1047951125100565_ref15","first-page":"1","article-title":"Endothelial-to-mesenchymal transition in autologous atrial tissue valves: a murine model study","volume":"12","author":"Miyazaki","year":"2022","journal-title":"JTCVS Open"},{"key":"S1047951125100565_ref17","first-page":"89","article-title":"Pediatric pulmonary valve reconstruction using autologous pericardium: 5-year results","volume":"117","author":"Ozaki","year":"2024","journal-title":"Ann Thorac Surg"},{"key":"S1047951125100565_ref18","first-page":"e385","article-title":"Cost analysis of pediatric cardiac intensive care in Europe","volume":"23","author":"Slater","year":"2022","journal-title":"Pediatr Crit Care Med"},{"key":"S1047951125100565_ref10","first-page":"174","article-title":"Embryonic origin and remodeling of the right atrial wall: implications for valve engineering","volume":"8","author":"Sugiura","year":"2021","journal-title":"J Cardiovasc Dev Dis"},{"key":"S1047951125100565_ref6","first-page":"1559","article-title":"Polytetrafluoroethylene monocusp valve in right ventricular outflow tract reconstruction: a word of caution","volume":"103","author":"Talwar","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"S1047951125100565_ref9","first-page":"269","article-title":"Durability of bioprosthetic valves in the pulmonary position: long-term follow-up of 397 implants","volume":"148","author":"Lee","year":"2014","journal-title":"J Thorac Cardiovasc Surg"},{"key":"S1047951125100565_ref19","first-page":"345","article-title":"Ventilator-associated pneumonia in congenital heart surgery: a 10-year cohort study","volume":"38","author":"Alimi","year":"2023","journal-title":"J Intensive Care Med"},{"key":"S1047951125100565_ref8","first-page":"437","article-title":"Bioresorbable pulmonary valve scaffolds: first-in-human trial","volume":"401","author":"Hoerstrup","year":"2023","journal-title":"Lancet"},{"key":"S1047951125100565_ref22","doi-asserted-by":"publisher","DOI":"10.25373\/ctsnet.24807867"},{"key":"S1047951125100565_ref26","first-page":"987","article-title":"Long-term outcomes of RVOT reconstruction in congenital heart defects: a 10-year follow-up study","volume":"44","author":"Harris","year":"2023","journal-title":"Pediatr Cardiol"},{"key":"S1047951125100565_ref25","first-page":"123","article-title":"Autologous tissue reconstruction in pediatric cardiac surgery: a systematic review of outcomes and complications","volume":"57","author":"Almousa","year":"2022","journal-title":"J Pediatr Surg"},{"key":"S1047951125100565_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200010000-00006"},{"key":"S1047951125100565_ref7","first-page":"145","article-title":"Monocusp valve repair in tetralogy of fallot: midterm outcomes","volume":"14","author":"Binsalamah","year":"2023","journal-title":"World J Pediatr Congenit Heart Surg"},{"key":"S1047951125100565_ref20","first-page":"211","article-title":"Cardiopulmonary bypass duration and neurodevelopment: a meta-analysis","volume":"165","author":"Gaynor","year":"2023","journal-title":"J Thorac Cardiovasc Surg"},{"key":"S1047951125100565_ref23","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezaa374"},{"key":"S1047951125100565_ref3","first-page":"112","article-title":"Repaired tetralogy of fallot: the roles of cardiovascular MRI","volume":"4","author":"Geva","year":"2011","journal-title":"JACC Cardiovasc Imaging"},{"key":"S1047951125100565_ref2","doi-asserted-by":"publisher","DOI":"10.1002\/bdr2.1589"},{"key":"S1047951125100565_ref24","first-page":"39","article-title":"Short-term outcome of polytetrafluoroethylene membrane valve versus transannular pericardial patch reconstruction of right ventricular outflow tract in tetralogy of fallot: a randomized controlled trial","volume":"36","author":"Rawat","year":"2020","journal-title":"Braz J Cardiovasc Surg"},{"key":"S1047951125100565_ref13","first-page":"642","article-title":"Extracellular matrix composition of human right atrial tissue: implications for valve reconstruction","volume":"61","author":"Deutsch","year":"2022","journal-title":"Eur J Cardiothorac Surg"},{"key":"S1047951125100565_ref21","first-page":"1892","article-title":"Arrhythmia risk after right atrial tissue harvesting: a systematic review","volume":"19","author":"Lee","year":"2022","journal-title":"Heart Rhythm"},{"key":"S1047951125100565_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.14860"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951125100565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T11:56:26Z","timestamp":1759492586000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951125100565\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":26,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S1047951125100565"],"URL":"https:\/\/doi.org\/10.1017\/s1047951125100565","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}