{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:48:14Z","timestamp":1787626094066,"version":"build-2736575974"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"unspecified","delay-in-days":15,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951125100590_as1\"><jats:title>Background:<\/jats:title><jats:p>Transcatheter pulmonary valve implantation has emerged as a minimally invasive and preferred therapeutic option for patients with dysfunction of previously repaired right ventricular outflow tracts. The Myval\u2122 Octacor valve is a new device designed for this purpose, though limited reports exist regarding its use in the pulmonary position.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100590_as2\"><jats:title>Aims:<\/jats:title><jats:p>To report the immediate and short-term outcomes of percutaneous pulmonary valve implantation using the Myval\u2122 Octacor valve in patients with severe right ventricular\u2013pulmonary artery conduit or pulmonary valve bioprosthesis dysfunction.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100590_as3\"><jats:title>Methods:<\/jats:title><jats:p>This was a single-centre retrospective review of data obtained from case files.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100590_as4\"><jats:title>Results:<\/jats:title><jats:p>The Myval\u2122 Octacor valve was used in ten patients with a mean age of 34.5 \u00b1 7.4 years. The median procedure duration and fluoroscopy time were 146 minutes and 30.5 minutes, respectively. The median Z-score for valves used was \u22120.5. The median right ventricular systolic pressure decreased from 68.5 mmHg pre-procedure to 33 mmHg post-procedure. The median peak instantaneous gradient across the right ventricular outflow tract or conduit decreased from 30 mmHg to 6.5 mmHg. There were no reported incidences of frame fracture, conduit rupture, device embolisation, or endocarditis.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100590_as5\"><jats:title>Conclusion:<\/jats:title><jats:p>This is the first UK experience of using the new-generation Myval\u2122 Octacor valve in percutaneous pulmonary valve implantation. The results demonstrate the valve\u2019s safety and clinical efficacy, with favourable outcomes in terms of procedural success, haemodynamic improvement, and echocardiographic findings.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951125100590","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T03:02:47Z","timestamp":1752634967000},"page":"1408-1414","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Early outcomes of Myval\u2122 Octacor transcatheter pulmonary valve implantation in dysfunctional right ventricular outflow tract conduits and pulmonary valve bioprostheses: a single-centre UK experience"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8478-8437","authenticated-orcid":false,"given":"Mohammed Kamal","family":"Badawy","sequence":"first","affiliation":[{"name":"University Hospitals of Leicester"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul","family":"Kalantre","sequence":"additional","affiliation":[{"name":"University Hospitals of Leicester"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5080-0119","authenticated-orcid":false,"given":"Marinos","family":"Kantzis","sequence":"additional","affiliation":[{"name":"University Hospitals of Leicester"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,7,16]]},"reference":[{"key":"S1047951125100590_ref22","first-page":"100452","article-title":"Transcatheter pulmonary valve replacement: a review of current valve technologies","volume":"1","author":"Patel","year":"2022","journal-title":"J Soc Cardiovasc Angiogr Interv"},{"key":"S1047951125100590_ref16","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1017\/S1047951121004650","article-title":"First experiences with Myval Transcatheter heart valve system in the treatment of severe pulmonary regurgitation in native right ventricular outflow tract and conduit dysfunction","volume":"32","author":"Odemis","year":"2022","journal-title":"Cardiol Young"},{"key":"S1047951125100590_ref1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/14779072.2018.1435273","article-title":"Transcatheter pulmonary valve implantation: will it replace surgical pulmonary valve replacement","volume":"16","author":"Kheiwa","year":"2018","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"S1047951125100590_ref18","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.acvd.2014.09.003","article-title":"Incidence and predictors of melody\u00ae valve endocarditis: a prospective study","volume":"108","author":"Malekzadeh-Milani","year":"2015","journal-title":"Arch Cardiovasc Dis"},{"key":"S1047951125100590_ref17","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.jcin.2018.01.239","article-title":"Transcatheter pulmonary valve replacement with the melody valve in small diameter expandable right ventricular outflow tract conduits","volume":"11","author":"Shahanavaz","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"key":"S1047951125100590_ref2","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0140-6736(00)02844-0","article-title":"Percutaneous replacement of pulmonary valve in a right ventricle to pulmonary artery prosthetic conduit with valve dysfunction","volume":"356","author":"Bonhoeffer","year":"2000","journal-title":"Lancet"},{"key":"S1047951125100590_ref10","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1007\/s00246-023-03398-1","article-title":"Multicenter experience for early and mid-term outcome of MyVal transcatheter pulmonary valve implantation","volume":"45","author":"Al Nasef","year":"2024","journal-title":"Pediatr Cardiol"},{"key":"S1047951125100590_ref23","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/j.jcin.2015.10.006","article-title":"Overexpansion of the SAPIEN 3 Transcatheter heart valve: a feasibility study","volume":"8","author":"Shivaraju","year":"2015","journal-title":"J Am Coll Cardiol Intv"},{"key":"S1047951125100590_ref24","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/24748706.2020.1742950","article-title":"Impact of over-expansion on SAPIEN 3 Transcatheter heart valve pericardial leaflets","volume":"4","author":"Sellers","year":"2020","journal-title":"Struct Heart"},{"key":"S1047951125100590_ref12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carrev.2024.01.016","article-title":"Safety and effectiveness of the novel Myval Octacor transcatheter heart valve in severe, symptomatic aortic valve stenosis \u2013 a real-world Indian experience (The OCTACOR India study)","volume":"63","author":"Jose","year":"2024","journal-title":"Cardiovasc Revasc Med"},{"key":"S1047951125100590_ref9","unstructured":"9. 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