{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T01:40:02Z","timestamp":1756777202389,"version":"3.44.0"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"unspecified","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951125100747_as1\"><jats:title>Background:<\/jats:title><jats:p>Pulmonary artery capacitance is a relatively novel measurement associated with adverse outcomes in pulmonary arterial hypertension. We sought to determine if preoperative indexed pulmonary artery capacitance was related to outcomes in paediatric heart transplant recipients, describe the changes in indexed pulmonary artery capacitance after transplantation, and compare its discriminatory ability to predict outcomes as compared to conventional predictors.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100747_as2\"><jats:title>Methods:<\/jats:title><jats:p>This was a retrospective study of paediatric patients who underwent heart transplant at our centre from July 2014 to May 2022. Variables from preoperative and postoperative clinical, catheterisation, and echo evaluations were recorded. The primary composite outcome measure included postoperative mortality, postoperative length of stay in the top quartile, and\/or evidence of end organ dysfunction.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100747_as3\"><jats:title>Results:<\/jats:title><jats:p>Of the 23 patients included in the analysis, 11 met the composite outcome. There was no statistical difference between indexed pulmonary artery capacitance values in patients who met the composite outcome [1.8 ml\/mmHg\/m<jats:sup>2<\/jats:sup> (interquartile 0.8, 2.4)] and those who did not [1.4 (interquartile 0.9, 1.7)], <jats:italic>p<\/jats:italic> = 0.17. There were no significant signs of post-operative right heart failure in either group. There was no significant difference between pre-transplant and post-transplant indexed pulmonary artery capacitance or indexed pulmonary vascular resistance.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951125100747_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Preoperative pulmonary artery capacitance was not associated with our composite outcome in paediatric heart transplant recipients. It did not appear to be additive to pulmonary vascular resistance in paediatric heart transplant patients. Pulmonary vascular disease did not appear to drive outcomes in this group.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951125100747","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T13:31:56Z","timestamp":1752154316000},"page":"1400-1407","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Impact of pulmonary artery capacitance index on early outcomes following paediatric heart transplantation"],"prefix":"10.1017","volume":"35","author":[{"given":"Angela M.","family":"Monafo","sequence":"first","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A.","family":"Harris","sequence":"additional","affiliation":[{"name":"Medical University of South Caroline"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn L.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoo N.","family":"Kavarana","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9920-6425","authenticated-orcid":false,"given":"Jason R.","family":"Buckley","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Savage","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8281-1522","authenticated-orcid":false,"given":"Anthony M.","family":"Hlavacek","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varsha M.","family":"Bandisode","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2928-6316","authenticated-orcid":false,"given":"John F.","family":"Rhodes","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina Shawn Jenkins Children\u2019s Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Costello","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7685-7877","authenticated-orcid":false,"given":"Shahryar M.","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"S1047951125100747_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.08.020"},{"key":"S1047951125100747_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2006.12.012"},{"key":"S1047951125100747_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1679"},{"key":"S1047951125100747_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03932.x"},{"key":"S1047951125100747_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.12.080"},{"key":"S1047951125100747_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.054"},{"key":"S1047951125100747_ref5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.112.968511"},{"key":"S1047951125100747_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2003.08.001"},{"key":"S1047951125100747_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.10.003"},{"key":"S1047951125100747_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2011.06.014"},{"key":"S1047951125100747_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.10.077"},{"key":"S1047951125100747_ref11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.085761"},{"key":"S1047951125100747_ref12","doi-asserted-by":"publisher","DOI":"10.5301\/ijao.5000556"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951125100747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T01:04:04Z","timestamp":1756775044000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951125100747\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1047951125100747"],"URL":"https:\/\/doi.org\/10.1017\/s1047951125100747","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}