{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:25:13Z","timestamp":1785414313616,"version":"3.56.0"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Kawasaki disease is a self-limiting vasculitis of unknown aetiology, and coronary artery lesions are its most common and serious complication. The Systemic Immune-Inflammation Index is a new biomarker of inflammation that may have prognostic value in Kawasaki disease. This study evaluated patients with Kawasaki disease and the prognostic role of Systemic Immune-Inflammation Index in coronary involvement. A total of 62 children with Kawasaki disease and 49 healthy controls were included. Systemic Immune-Inflammation Index was calculated as: neutrophils \u00d7 platelets\/lymphocytes). Systemic Immune-Inflammation Index was also significantly higher in Kawasaki disease patients than controls (2373 \u00b1 2040 vs. 300 \u00b1 218,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001). Subgroup analysis of the Kawasaki disease patients showed that Systemic Immune-Inflammation Index was significantly higher in patients with coronary artery lesions than in those without (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05). In conclusion, Systemic Immune-Inflammation Index is a composite inflammatory biomarker easily obtained from routine blood parameters and may be an independent predictor of coronary artery involvement in Kawasaki disease.\n                  <\/jats:p>","DOI":"10.1017\/s1047951125109852","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T09:38:37Z","timestamp":1760434717000},"page":"2265-2269","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating patients with Kawasaki disease: can the systemic immune inflammation index predict coronary involvement?"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7211-327X","authenticated-orcid":false,"given":"Merve","family":"Korkut O\u011fuz","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01etz1309","id-type":"ROR","asserted-by":"publisher"}],"name":"Pamukkale University School of 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there a role for laboratory parameters in predicting coronary artery involvement in kawasaki disease?","volume":"234","author":"Yalcinkaya","year":"2022","journal-title":"Klin Padiatr"},{"key":"S1047951125109852_ref16","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14141495"},{"key":"S1047951125109852_ref13","first-page":"9213074","article-title":"Mean platelet volume (MPV): new perspectives for an old marker in the course and prognosis of inflammatory conditions","volume":"17","author":"Korniluk","year":"2019","journal-title":"Mediators 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