{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T20:32:40Z","timestamp":1794256360973,"version":"4.9.0"},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"unspecified","delay-in-days":21,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951125110548_as1\">\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To evaluate the right ventricle function by conventional echocardiographic methods and strain analysis in the long term after balloon pulmonary valvuloplasty. In addition, we investigated the relationship between pulmonary regurgitation, demographic data at the time of the procedure, and right ventricle dysfunction in late follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125110548_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The records of patients submitted to balloon pulmonary valvuloplasty from 2001 to 2015 in a single centre were reviewed. From that sample, a revised cohort was formed, and the patients were submitted to clinical and echocardiographic evaluations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125110548_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The retrospective and the revised cohort analyses included 73 and 18 patients, respectively. In the follow-up, pulmonary regurgitation was observed in all patients, and there was a significant worsening of its magnitude over time (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001); the severity of pulmonary regurgitation was associated with balloon pulmonary valvuloplasty performed in patients with weight &lt; 3 kg (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.03), body surface area &lt; 0.3 m\n                      <jats:sup>2<\/jats:sup>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.04), and &lt; 1 year of age (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.006). Global longitudinal systolic strain of the right ventricle was abnormal in 8 of 18 patients, and conventional methods were abnormal in 2 of 18 patients (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001). There was a significant relationship between severe pulmonary regurgitation and right ventricle dysfunction detected only by strain evaluation (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125110548_as4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      The severity of pulmonary regurgitation was related to the impairment of right ventricle function detected by strain. The predictors of pulmonary regurgitation severity in late follow-up were age &lt; 1 year, weight &lt; 3 kg, and body surface area &lt; 0.3 m\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951125110548","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T08:34:55Z","timestamp":1766392495000},"page":"2544-2549","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Right ventricular systolic function and its relationship with pulmonary regurgitation in late follow-up of balloon pulmonary valvuloplasty"],"prefix":"10.1017","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2896-2751","authenticated-orcid":false,"given":"Luciana Silveira Nina","family":"de 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Ambrosio","family":"Moises","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02k5swt12","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidade Federal de S\u00e3o Paulo, S\u00e3o Paula"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"S1047951125110548_ref2","first-page":"747","article-title":"Percutaneous balloon pulmonary valvuloplasty: state of the art","volume":"69","author":"Rao","year":"2007","journal-title":"Cath Cardiovasc 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