{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:20:37Z","timestamp":1785435637719,"version":"3.56.0"},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"unspecified","delay-in-days":18,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951125110858_as1\">\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Idiopathic infantile arterial calcification is a rare autosomal recessive disorder characterised by extensive calcification and proliferation of the intimal layer of the large and medium sized arteries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125110858_as2\">\n                    <jats:title>Methods and objectives:<\/jats:title>\n                    <jats:p>The diagnosis is usually made at autopsy or in the neonatal period, when there is cardiac failure. Prenatal diagnosis is possible in the latter half of pregnancy when there are hyperechoic vessel walls, hypertrophied ventricular musculature, and nonimmune fetal hydrops. The number of cases diagnosed before birth is low.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125110858_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>This study presents a 27-week pregnant patient diagnosed with widespread calcification in the aorta and pulmonary arteries, severe pericardial effusion, and hydrops fetalis during fetal echocardiographic examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125110858_as4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case report reminds paediatric cardiologists, radiologists, and perinatologists that they should be familiar with widespread arterial calcification. It emphasises that idiopathic infantile arterial calcification, a very rare condition, should be considered among the etiologic factors when hydrops fetalis is detected on ultrasound.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951125110858","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T08:28:52Z","timestamp":1768811332000},"page":"171-173","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["A very rare cause of hydrops fetalis: idiopathic infantile arterial calcification"],"prefix":"10.1017","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3267-8161","authenticated-orcid":false,"given":"Mecnun","family":"Cetin","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/041jyzp61","id-type":"ROR","asserted-by":"publisher"}],"name":"Yuzuncu Yil University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"S1047951125110858_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2023.07.019"},{"key":"S1047951125110858_ref3","first-page":"1","article-title":"Antenatal diagnosis of idiopathic infantile arterial calcification (IIAC): a single centre experience and review of the literature","volume":"3","author":"Mulcahy","year":"2019","journal-title":"J Congenit cardio"},{"key":"S1047951125110858_ref5","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.1032519"},{"key":"S1047951125110858_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-022-05364-0"},{"key":"S1047951125110858_ref2","first-page":"1","article-title":"Case report: a novel genetic mutation causes idiopathic infantile arterial calcification in preterm infants","volume":"21","author":"Yunfeng","year":"2021","journal-title":"Front Genet"},{"key":"S1047951125110858_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-017-0370-3"},{"key":"S1047951125110858_ref8","doi-asserted-by":"publisher","DOI":"10.3941\/jrcr.v9i11.2622"},{"key":"S1047951125110858_ref9","first-page":"167","article-title":"Generalized arterial calcification of infancy: treatment with bisphosphonates","volume":"5","author":"Ramjan","year":"2009","journal-title":"Nat Clin Pract Endocrinol Metabol"},{"key":"S1047951125110858_ref1","first-page":"15","article-title":"Idiopathic infantile arterial calcification: an autopsy evaluation","volume":"7","author":"Mune","year":"2023","journal-title":"IHJ Cardiovas Case Rep (CVCR)"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951125110858","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T04:32:38Z","timestamp":1775795558000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951125110858\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S1047951125110858"],"URL":"https:\/\/doi.org\/10.1017\/s1047951125110858","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}