{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:03:11Z","timestamp":1785416591397,"version":"3.56.0"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"unspecified","delay-in-days":25,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951125111062_as1\">\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aimed to identify echocardiographic predictors of successful weaning from extracorporeal membrane oxygenation in paediatric and congenital heart disease patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125111062_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We retrospectively analyzed pediatric patients who underwent venoarterial extracorporeal membrane oxygenation for cardiogenic shock or postoperative support between March 2018 and September 2023. Clinical and echocardiographic variables assessed at the time of weaning evaluation were compared between patients who were successfully weaned and those who were not.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125111062_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among the 46 enrolled patients, 31 were successfully weaned from extracorporeal membrane oxygenation. The mean age at extracorporeal membrane oxygenation initiation was 9.6 \u00b1 13.9 years, and the mean duration of support was 12.3 \u00b1 12.1 days. Patients in the successfully weaned group had significantly higher left ventricular ejection fraction (50.9 \u00b1 16.4% vs. 27.3 \u00b1 18.7%,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) and higher velocity time integral at the left ventricular outflow tract (12.3 \u00b1 8.0 cm vs. 4.1 \u00b1 3.6 cm,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001) compared with the unsuccessfully weaned group. The cutoff values for predicting successful weaning were a left ventricular ejection fraction of 43.03% (sensitivity, 74.2%; specificity, 86.7%) and a velocity time integral of 4.45 cm (sensitivity, 92.0%; specificity, 66.7%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125111062_as4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Left ventricular ejection fraction and velocity time integral provide valuable echocardiographic information for predicting successful weaning from extracorporeal membrane oxygenation in pediatric patients and may support clinical decision-making during weaning assessments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951125111062","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T10:52:22Z","timestamp":1769424742000},"page":"4-9","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Echocardiographic predictors of successful weaning from extracorporeal membrane oxygenation in paediatric and CHD patients with cardiogenic shock"],"prefix":"10.1017","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4949-9688","authenticated-orcid":false,"given":"Hye Won","family":"Kwon","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01z4nnt86","id-type":"ROR","asserted-by":"publisher"}],"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Gun","family":"Kwak","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01z4nnt86","id-type":"ROR","asserted-by":"publisher"}],"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sungkyu","family":"Cho","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01z4nnt86","id-type":"ROR","asserted-by":"publisher"}],"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2837-7929","authenticated-orcid":false,"given":"Woong-Han","family":"Kim","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01z4nnt86","id-type":"ROR","asserted-by":"publisher"}],"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi Kyoung","family":"Song","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Yun","family":"Lee","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7880-280X","authenticated-orcid":false,"given":"Gi Beom","family":"Kim","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Jung","family":"Bae","sequence":"additional","affiliation":[{"name":"Seoul National University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"S1047951125111062_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.03.019"},{"key":"S1047951125111062_ref1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000002128"},{"key":"S1047951125111062_ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-04249-w"},{"key":"S1047951125111062_ref13","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000001431"},{"key":"S1047951125111062_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01912-9"},{"key":"S1047951125111062_ref11","first-page":"682","article-title":"Extracorporeal membranous oxygenation support for acute fulminant myocarditis: analysis of a single center\u2019s experience","volume":"40","author":"Hsu","year":"2011","journal-title":"Eur J Cardiothorac 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methods","volume":"35","author":"Cecconi","year":"2021","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"S1047951125111062_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-011-2358-2"}],"container-title":["Cardiology in the 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