{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:27:58Z","timestamp":1790018878674,"version":"4.0.1"},"reference-count":36,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"unspecified","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951125111268_as1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Exercise capacity (VO\n                      <jats:sub>2peak<\/jats:sub>\n                      ) predicts mortality in adult patients with CHD. There is a lack of paediatric exercise capacity data based on specific CHD lesions, limiting the ability to contextualise interpretation based on expected performance during testing. The primary aim of this study was to establish VO\n                      <jats:sub>2peak<\/jats:sub>\n                      percentiles for paediatric patients with repaired CHD undergoing treadmill-based cardiopulmonary exercise testing (CPET).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125111268_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective analysis of CPET data from 2004 to 2022. CPETs were analysed for patients with CHD aged 6\u201318 years. Patients with repaired CHD were categorised based on their most haemodynamically significant CHD lesion. Percentiles and age-based trends were plotted for each group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125111268_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 887 patients were included. CHD patients were divided into ten diagnostic subgroups. The mean percent expected VO\n                      <jats:sub>2peak<\/jats:sub>\n                      for each of the subgroups were as follows: Atrial and ventricular septal defect (94.5 \u00b1 25.1%), pulmonary valve repair (88.1 \u00b1 18.4%), aortic valve repair (92.7 \u00b1 16.4%), tricuspid and mitral valve repair (81.3 \u00b1 20.4%), coarctation of the aorta (93.6 \u00b1 18.8%), transposition of the great arteries (90.5 \u00b1 19.4%), double outlet right ventricle and truncus arteriosus (80.5 \u00b1 16.2%), tetralogy of Fallot (85.6 \u00b1 20.9%), left ventricle dominant Fontan (74.7 \u00b1 18.3%), and right ventricle dominant Fontan (75.7 \u00b1 16.7%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951125111268_as4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      There is a varying degree of reduced exercise capacity in paediatric patients with repaired CHD. Univentricular hearts and tricuspid and mitral valve repair have the lowest VO\n                      <jats:sub>2peak<\/jats:sub>\n                      . These CHD-specific percentiles may help providers risk-stratify and counsel patients with CHD.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951125111268","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T04:35:36Z","timestamp":1770179736000},"page":"244-251","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Reference standards and diagnosis-specific trends in cardiorespiratory fitness in paediatric patients with repaired CHD"],"prefix":"10.1017","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4243-6676","authenticated-orcid":false,"given":"Garett J.","family":"Griffith","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/000e0be47","id-type":"ROR","asserted-by":"publisher"}],"name":"Northwestern University Feinberg School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Wang","sequence":"additional","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0012-7750","authenticated-orcid":false,"given":"Kendra","family":"Ward","sequence":"additional","affiliation":[{"name":"Ann & Robert H. Lurie Children\u2019s Hospital of Chicago"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"S1047951125111268_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.02.140"},{"key":"S1047951125111268_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.07.010"},{"key":"S1047951125111268_ref5","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2018-000812"},{"key":"S1047951125111268_ref23","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000001559"},{"key":"S1047951125111268_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.12.076"},{"key":"S1047951125111268_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.06.029"},{"key":"S1047951125111268_ref25","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1984.129.2P2.S47"},{"key":"S1047951125111268_ref15","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000866"},{"key":"S1047951125111268_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.03.582"},{"key":"S1047951125111268_ref17","doi-asserted-by":"publisher","DOI":"10.1177\/2047487313505242"},{"key":"S1047951125111268_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1275-5"},{"key":"S1047951125111268_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2023.11.061"},{"key":"S1047951125111268_ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2017.04.009"},{"key":"S1047951125111268_ref21","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1984.129.2P2.S47"},{"key":"S1047951125111268_ref7","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-312339"},{"key":"S1047951125111268_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.11.092"},{"key":"S1047951125111268_ref22","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwad054"},{"key":"S1047951125111268_ref26","doi-asserted-by":"publisher","DOI":"10.1123\/pes.7.1.49"},{"key":"S1047951125111268_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.03.582"},{"key":"S1047951125111268_ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.11.009"},{"key":"S1047951125111268_ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2017.10.010"},{"key":"S1047951125111268_ref35","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.124.038200"},{"key":"S1047951125111268_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.12.046"},{"key":"S1047951125111268_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2023.113770"},{"key":"S1047951125111268_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1275-5"},{"key":"S1047951125111268_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2017.05.005"},{"key":"S1047951125111268_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-022-04648-9"},{"key":"S1047951125111268_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2023.11.061"},{"key":"S1047951125111268_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-019-09867-1"},{"key":"S1047951125111268_ref29","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr461"},{"key":"S1047951125111268_ref27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0803.2011.00500.x"},{"key":"S1047951125111268_ref36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-5922.2011.00306.x"},{"key":"S1047951125111268_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(19)30402-X"},{"key":"S1047951125111268_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.002846"},{"key":"S1047951125111268_ref34","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12661"},{"key":"S1047951125111268_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)01054-8"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951125111268","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T12:37:44Z","timestamp":1783082264000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951125111268\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S1047951125111268"],"URL":"https:\/\/doi.org\/10.1017\/s1047951125111268","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}