{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:17:39Z","timestamp":1785410259416,"version":"3.56.0"},"reference-count":6,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"unspecified","delay-in-days":26,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We present the case of an 8-year-old male with frequent premature ventricular contractions and mild left ventricular dysfunction, who was found to carry heterozygous variants in both\n                    <jats:italic>FLNC<\/jats:italic>\n                    and\n                    <jats:italic>CTNNA3<\/jats:italic>\n                    . Medical therapy resulted in improved systolic function and reduced arrhythmia burden. This rare combination suggests a potential genotype\u2013phenotype correlation in paediatric arrhythmogenic cardiomyopathy.\n                  <\/jats:p>","DOI":"10.1017\/s104795112611186x","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T09:35:23Z","timestamp":1774604123000},"page":"645-647","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Paediatric patient with\n                    <i>FLNC<\/i>\n                    and\n                    <i>CTNNA3<\/i>\n                    variants presenting with frequent premature ventricular contractions and systolic dysfunction: a case report"],"prefix":"10.1017","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7665-5252","authenticated-orcid":false,"given":"Damla","family":"G\u00f6k\u00e7eer Akbulut","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05jxvg504","id-type":"ROR","asserted-by":"publisher"}],"name":"Kanuni Sultan Suleyman Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4012-3278","authenticated-orcid":false,"given":"Helen","family":"Bornaun","sequence":"additional","affiliation":[{"name":"Kanuni Sultan Suleyman Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamide","family":"Sayg\u0131l\u0131","sequence":"additional","affiliation":[{"name":"Kanuni Sultan Suleyman Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6111-1789","authenticated-orcid":false,"given":"Demet","family":"Tosun","sequence":"additional","affiliation":[{"name":"Kanuni Sultan Suleyman Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,3,27]]},"reference":[{"key":"S104795112611186X_ref2","doi-asserted-by":"publisher","DOI":"10.2147\/TACG.S383446"},{"key":"S104795112611186X_ref5","first-page":"101027","article-title":"A child with dilated cardiomyopathy and homozygous splice site variant in FLNC gene","volume":"38","author":"Alsubhi","year":"2023","journal-title":"Mol Genet Metab Rep"},{"key":"S104795112611186X_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/cge.13594"},{"key":"S104795112611186X_ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s40246-024-00683-9"},{"key":"S104795112611186X_ref1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9030878"},{"key":"S104795112611186X_ref6","first-page":"332","article-title":"Cardiovascular involvement in pediatric FLNC variants: a case series of fourteen patients","volume":"9","author":"Baban","year":"2022","journal-title":"J Cardiovasc Dev Dis"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S104795112611186X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T13:08:52Z","timestamp":1776085732000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S104795112611186X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S104795112611186X"],"URL":"https:\/\/doi.org\/10.1017\/s104795112611186x","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}