{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:33:33Z","timestamp":1785429213525,"version":"3.56.0"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"unspecified","delay-in-days":36,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951126112219_as1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Acute kidney injury after infant congenital cardiac surgery is common and worsens outcomes. Renal resistive index may aid early postoperative risk stratification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951126112219_as2\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate a single six-hour postoperative renal resistive index as an early acute kidney injury marker and its association with postoperative haemodynamic support.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951126112219_as3\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A prospective single-centre cohort of neonates and infants &lt; 12 months (\n                      <jats:italic>n<\/jats:italic>\n                      = 41) was classified as acute kidney injury (\n                      <jats:italic>n<\/jats:italic>\n                      = 19) or non-acute kidney injury (\n                      <jats:italic>n<\/jats:italic>\n                      = 22). Renal resistive index was measured at six hours (primary), 48 hr, and discharge. Postoperative acute kidney injury was diagnosed using Kidney Disease: Improving Global Outcomes serum creatinine and urine output criteria over 48 hr. Vasoactive\u2013inotropic score was recorded, and discrimination was assessed using receiver operating characteristic analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951126112219_as4\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At six hours, renal resistive index was higher in acute kidney injury vs. non-acute kidney injury (0.84 \u00b1 0.07 vs. 0.74 \u00b1 0.08;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.0002) with good unadjusted discrimination (area under the curve 0.83; 95% CI 0.68\u20130.97). Surgical complexity was higher in the acute kidney injury group (median STAT 4 vs. 3). At 48 hr, renal resistive index remained higher (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.017; area under the curve 0.70), while discharge values were similar (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.18; area under the curve 0.62). A six-hour renal resistive index &lt; 0.80 excluded moderate-to-severe acute kidney injury, whereas \u2265 0.86 identified a higher risk. Vasoactive\u2013inotropic score at 48 hr was higher in acute kidney injury (7.2 \u00b1 8.1 vs. 1.9 \u00b1 3.4;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.009), and six-hour renal resistive index correlated modestly with inotropic burden (\n                      <jats:italic>r<\/jats:italic>\n                      = 0.56;\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Three acute kidney injury infants required peritoneal dialysis, all with six-hour renal resistive index \u2265 0.90.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951126112219_as5\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>A six-hour renal resistive index may help early acute kidney injury risk assessment after infant cardiac surgery. External validation is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951126112219","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T06:02:27Z","timestamp":1778133747000},"page":"789-794","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Six-hour renal resistive index as an early marker of acute kidney injury after infant cardiac surgery: a prospective cohort study"],"prefix":"10.1017","volume":"36","author":[{"given":"Ahmed R.","family":"Elsaoudi","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/009djsq06","id-type":"ROR","asserted-by":"publisher"}],"name":"King Abdulaziz Cardiac Center"},{"name":"King Abdullah International Medical Research 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