{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:49:24Z","timestamp":1785408564884,"version":"3.56.0"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"unspecified","delay-in-days":27,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Children with CHD who require surgical or catheter-based intervention in the neonatal period are increasingly surviving into childhood; however, their long-term health-related quality of life remains insufficiently characterised, particularly in the preschool period. We aimed to evaluate health-related quality of life in preschool-aged children treated for CHD during the neonatal period and to identify associated clinical and sociodemographic factors. This retrospective, cross-sectional case\u2013control study included 50 children aged 4\u20137 years with a history of neonatal CHD intervention and 100 age-matched healthy controls. Health-related quality of life was assessed using the parent-reported Kiddy-KINDL questionnaire. Demographic, clinical, and socio-economic data were obtained from medical records and structured parental interviews. Group comparisons were performed using appropriate parametric or nonparametric tests, and factors associated with health-related quality of life were analysed using multiple linear regression. Total Kiddy-KINDL scores were significantly lower in children with CHD compared with controls (55.4 \u00b1 8.8 vs. 62.3 \u00b1 6.5,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001). All health-related quality of life subdomains, including physical well-being, emotional well-being, self-esteem, family relations, social functioning, and kindergarten adjustment, were significantly impaired in the CHD group (all\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05). In multivariable analysis, maternal and paternal education levels and household income were independent predictors of health-related quality of life, whereas the surgical risk category was not significantly associated with health-related quality of life outcomes. Preschool children treated for CHD in the neonatal period demonstrate significantly reduced health-related quality of life compared with healthy peers, with socio-economic factors playing a more prominent role than clinical disease severity. These findings underscore the importance of incorporating family-centred and socioeconomically sensitive strategies into the long-term follow-up of children with CHD.\n                  <\/jats:p>","DOI":"10.1017\/s1047951126113110","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T06:58:17Z","timestamp":1779951497000},"page":"1045-1050","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Quality of life in preschool children with CHD treated in the neonatal period: kiddy-KINDL outcomes and associated factors"],"prefix":"10.1017","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5579-2791","authenticated-orcid":false,"given":"Merve Nur","family":"Kurt Albayrak","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01nk6sj42","id-type":"ROR","asserted-by":"publisher"}],"name":"Ministry of Health T\u00fcrkiye, Ankara Etlik City Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2634-2562","authenticated-orcid":false,"given":"Dilek","family":"Dilli","sequence":"additional","affiliation":[{"name":"University of Health Sciences T\u00fcrkiye, Ministry of Health T\u00fcrkiye, Ankara Etlik City Hospital, Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"S1047951126113110_ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-020-01615-6"},{"key":"S1047951126113110_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182949a2e"},{"key":"S1047951126113110_ref12","doi-asserted-by":"publisher","DOI":"10.5152\/TurkPediatriArs.2018.6428"},{"key":"S1047951126113110_ref17","doi-asserted-by":"publisher","DOI":"10.2223\/JPED.1958"},{"key":"S1047951126113110_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.025"},{"key":"S1047951126113110_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.01.071"},{"key":"S1047951126113110_ref18","first-page":"456","article-title":"3-6 ya\u015f grubu \u00e7ocu\u011fun akut bir hastal\u0131k nedeniyle hastaneye yat\u0131\u015fa kar\u015f\u0131 davran\u0131\u015fsal tepkilerinin belirlenmesi","volume":"7","author":"Ba\u015fbakkal","year":"2010","journal-title":"Uluslararas\u0131 \u0130nsan Bilimleri Dergisi"},{"key":"S1047951126113110_ref15","first-page":"1264","article-title":"The influence of mothers\u2019 educational level on children\u2019s comprehensive quality","volume":"8","author":"Yu","year":"2023","journal-title":"J Educ Humanit Soc Sci"},{"key":"S1047951126113110_ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-3778"},{"key":"S1047951126113110_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1201-x"},{"key":"S1047951126113110_ref6","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008853819715"},{"key":"S1047951126113110_ref7","first-page":"148","article-title":"Health-related quality of life in children and adolescents in Germany: results of the BELLA study","volume":"16","author":"Ravens-Sieberer","year":"2007","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"S1047951126113110_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951124026155"},{"key":"S1047951126113110_ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951115000086"},{"key":"S1047951126113110_ref16","first-page":"149","article-title":"Quality of Life of Children Between 5 and 7 Years and Affecting Factors.","volume":"23","author":"Da\u011ftekin","year":"2023","journal-title":"J Child."},{"key":"S1047951126113110_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(15)60544-7"},{"key":"S1047951126113110_ref9","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-3435"},{"key":"S1047951126113110_ref14","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.010616"},{"key":"S1047951126113110_ref5","first-page":"409","article-title":"\u00c7ocuklar \u0130\u00e7in Genel Ama\u00e7l\u0131 Sa\u011fl\u0131kla \u0130lgili Ya\u015fam Kalitesi \u00d6l\u00e7e\u011fi (Kid-KINDL) T\u00fcrk\u00e7e s\u00fcr\u00fcm\u00fcn\u00fcn psikometrik \u00f6zellikleri","volume":"19","author":"Eser","year":"2008","journal-title":"T\u00fcrk Psikiyatri Dergisi"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951126113110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T11:35:15Z","timestamp":1782128115000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951126113110\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S1047951126113110"],"URL":"https:\/\/doi.org\/10.1017\/s1047951126113110","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}