{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:04:37Z","timestamp":1789729477015,"version":"4.0.1"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"abstract":"Abstract<\/jats:title>\n \n Introduction:<\/jats:title>\n Discrepancies between preoperative echocardiographic diagnosis and intraoperative surgical findings for incomplete atrioventricular septal defects are frequently encountered. We assess the frequency of diagnostic discordance and its impact, focusing on subtype-specific predictors of the postoperative course.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n We reviewed 172 patients post repair of incomplete atrioventricular septal defects at a single institution between November 2000\u2013February 2025, including transitional atrioventricular septal defects (\n n<\/jats:italic>\n = 74), partial atrioventricular septal defects (\n n<\/jats:italic>\n = 71), and primum atrial septal defect with isolated left atrioventricular valve cleft (\n n<\/jats:italic>\n = 27). Preoperative echocardiographic diagnoses were compared with intraoperative surgical diagnoses to determine diagnostic discordance and assess impact.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Baseline characteristics were similar across subtypes. Transitional atrioventricular septal defects were associated with a higher prevalence of syndromic diagnoses (52.7% versus 33.8% versus 22.2%,\n p<\/jats:italic>\n = 0.008) and greater preoperative ventricular dilation (LVIDd\n Z<\/jats:italic>\n -score \u22120.88 versus \u22121.70 versus \u22121.70,\n p<\/jats:italic>\n = 0.031). Diagnostic discordance occurred most frequently in partial atrioventricular septal defects (74.6%), followed by primum atrial septal defect with isolated left atrioventricular valve cleft (37.0%) and transitional atrioventricular septal defects (13.5%) (\n p<\/jats:italic>\n < 0.001). Transitional atrioventricular septal defect repairs were associated with longer cardiopulmonary bypass and cross-clamp times, prolonged ventilation, and longer hospital stays (all\n p<\/jats:italic>\n < 0.05). Residual shunt was more frequent in transitional atrioventricular septal defects early postoperatively and at the last follow-up (\n p<\/jats:italic>\n < 0.001). One death was observed in the partial atrioventricular septal defects group, reintervention rates were similar across subtypes (\n p<\/jats:italic>\n = 0.643), and follow-up duration differed modestly between groups (\n p<\/jats:italic>\n = 0.047).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The high rate of diagnostic discordance reflects inherent challenges in preoperative classification and suggests that a simplified, clinically oriented nomenclature may improve communication, surgical planning, and outcome prediction.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/s104795112612397x","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:31:31Z","timestamp":1789727491000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Transitional atrioventricular septal defect: diagnostic variability and its clinical significance"],"prefix":"10.1017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1968-1868","authenticated-orcid":false,"given":"Aybala","family":"Tongut","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03wa2q724","id-type":"ROR","asserted-by":"publisher"}],"name":"Children\u2019s National Hospital"},{"name":"Children\u2019s National Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep B.","family":"Eren","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03wa2q724","id-type":"ROR","asserted-by":"publisher"}],"name":"Children\u2019s National Hospital"},{"name":"Children\u2019s National Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Haverty","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03wa2q724","id-type":"ROR","asserted-by":"publisher"}],"name":"Children\u2019s National Hospital"},{"name":"Children\u2019s National Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonia C.","family":"Carter","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03wa2q724","id-type":"ROR","asserted-by":"publisher"}],"name":"Children\u2019s National Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssia","family":"Venna","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03wa2q724","id-type":"ROR","asserted-by":"publisher"}],"name":"Children\u2019s National Hospital"},{"name":"Children\u2019s National Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manan","family":"Desai","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03wa2q724","id-type":"ROR","asserted-by":"publisher"}],"name":"Children\u2019s National Hospital"},{"name":"Children\u2019s National 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in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S104795112612397X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:31:32Z","timestamp":1789727492000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S104795112612397X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,18]]},"references-count":21,"alternative-id":["S104795112612397X"],"URL":"https:\/\/doi.org\/10.1017\/s104795112612397x","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,18]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. 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