{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T03:26:44Z","timestamp":1793849204339,"version":"4.6.1"},"reference-count":46,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"unspecified","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":28,"URL":"https:\/\/www.cambridge.org\/tdm\/tdmrep-policy.json"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S104795112612410X_as1\">\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To describe the quality of life and moderate-to-vigorous physical activity level among children with CHD compared to children without CHD and to examine whether the association between these variables is modified by CHD or gender.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S104795112612410X_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This cross-sectional analysis draws from a larger longitudinal study and included participants aged 5\u201310 years with or without any CHD and living in British Columbia, Canada. Parents\/guardians completed the parent-proxy PedsQL 4.0 Generic Core Scales, providing a PedsQL Total Score out of 100. Children wore an Ametris GT3X accelerometer for 7 consecutive days to measure moderate-to-vigorous physical activity (min\/day). Generalised linear regression models were used for group and gender comparisons. An adjusted linear regression model was used to examine the association between physical activity and quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S104795112612410X_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      166 children (41% girls;\n                      <jats:italic>n<\/jats:italic>\n                      = 78 CHD,\n                      <jats:italic>n<\/jats:italic>\n                      = 88 non-CHD) were included in the analysis. Children with CHD had poorer PedsQL Total Scores (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.002) and accumulated less moderate-to-vigorous physical activity than the non-CHD group (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.008). Among children with CHD, girls accumulated less moderate-to-vigorous physical activity than boys (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) and had poorer PedsQL Total Scores than boys (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.035). The association between moderate-to-vigorous physical activity (min\/day) and PedsQL Total Score was significantly modified by CHD (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.012), with a positive association found for children with CHD (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      = 0.17 [95% confidence interval: 0.04, 0.29],\n                      <jats:italic>p<\/jats:italic>\n                      = 0.011), which was not modified by gender (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.241).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S104795112612410X_as4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>These findings highlight the need to support the physical and psychosocial health of children with CHD, particularly girls with CHD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s104795112612410x","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:39:49Z","timestamp":1790671189000},"page":"1848-1854","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Physical activity and quality of life among children with CHD: a cross-sectional analysis"],"prefix":"10.1017","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3593-2156","authenticated-orcid":false,"given":"Tyrell C.","family":"Sideroff","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03rmrcq20","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of British Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Collins","sequence":"additional","affiliation":[{"name":"BC Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurin","family":"Izzati Binti Saiful Baharin","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03rmrcq20","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of British Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia H.","family":"Crowther","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03rmrcq20","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of British Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Harris","sequence":"additional","affiliation":[{"name":"BC Children\u2019s Hospital"},{"name":"The University of British Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3811-2465","authenticated-orcid":false,"given":"Christine","family":"Voss","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03rmrcq20","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of British Columbia"},{"name":"The University of British Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"S104795112612410X_ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-017-1645-2"},{"key":"S104795112612410X_ref8","doi-asserted-by":"publisher","DOI":"10.1037\/hea0000653"},{"key":"S104795112612410X_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.23297"},{"key":"S104795112612410X_ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-019-02220-1"},{"key":"S104795112612410X_ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-017-1730-6"},{"key":"S104795112612410X_ref14","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-14-32"},{"key":"S104795112612410X_ref15","unstructured":"15. 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}