{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T17:06:21Z","timestamp":1706202381116},"reference-count":141,"publisher":"Cambridge University Press (CUP)","issue":"S7","license":[{"start":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T00:00:00Z","timestamp":1415318400000},"content-version":"unspecified","delay-in-days":3750,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CNS Spectr."],"published-print":{"date-parts":[[2004,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Bipolar disorder in women presents special diagnostic and treatment challenges to the clinician. The presentation of female bipolar may resemble depressive disorders, comorbid Axis I disorders, Axis II personality disorders, behavioral dysregulation, or general medical disorders; thus, it is critically important for clinicians to assess for a history of hypomania or mania when determining diagnosis in any woman presenting with psychological symptoms. Several gender differences may exist in the epidemiology and symptomatology of bipolar disorder, and each must be kept in mind during assessment. Rapid cycling and mixed states have been associated with female gender and may present diagnostic challenges as each often presents as major depression. Symptoms of postpartum psychosis tend to differ from the symptoms typically seen in bipolar mania; therefore, if postpartum psychosis is actually a manifestation of bipolar disorder, accurate diagnosis depends upon a knowledge of these differences. Special treatment considerations for bipolar disorder in women involve interactions between the illness and the female reproductive cycle. A risk of fetal malformation exists when some mood-stabilizing agents are used during conception and\/or during the first trimester of pregnancy. Neurobehavioral teratogenicity and neonatal toxicity is also possible. Careful treatment management is necessary to reduce the risks to the fetus\/infant and to effectively manage bipolar disorder in the mother. In treating women with bipolar disorder, clinicians should discuss the issue of pregnancy and associated risks of treatment versus no treatment with every patient of reproductive age. Further studies are needed on gestational timing and exposure to mood-stabilizing agents, especially newer agents recently approved or currently being considered for the treatment of bipolar disorder.<\/jats:p>","DOI":"10.1017\/s1092852900002327","type":"journal-article","created":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T00:41:01Z","timestamp":1470098461000},"page":"5-18","source":"Crossref","is-referenced-by-count":15,"title":["Bipolar Disorders: Special Diagnostic and Treatment Considerations in Women"],"prefix":"10.1017","volume":"9","author":[{"given":"Susan L.","family":"McElroy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,11,7]]},"reference":[{"key":"S1092852900002327_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00322-1"},{"key":"S1092852900002327_ref087","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5859.138"},{"key":"S1092852900002327_ref102","volume-title":"Drugs in Pregnancy and Lactation","author":"Briggs","year":"2002"},{"key":"S1092852900002327_ref061","first-page":"207","article-title":"Study on the relationship between psychiatric symptoms and sexual cycle","volume":"8","author":"Ota","year":"1954","journal-title":"Folia Psychiatrica Neurol Japan"},{"key":"S1092852900002327_ref088","first-page":"924","article-title":"Lithium carbonate intake during pregnancy leading to large goiter in a premature infant","volume":"131","author":"Nars","year":"1977","journal-title":"Am J Dis Child."},{"key":"S1092852900002327_ref084","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1994.03510260078033"},{"key":"S1092852900002327_ref073","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.6.913"},{"key":"S1092852900002327_ref134","first-page":"825","article-title":"Elevated serum LH and androgens in affective disorder related to the menstrual cycle: with reference to polycystic ovary syndrome","volume":"47","author":"Matsunaga","year":"1993","journal-title":"Jpn J Psychiatry Neurol."},{"key":"S1092852900002327_ref098","first-page":"149","article-title":"Consensus guidelines: preconception counseling, management, and care of pregnant women wiThepilepsy","volume":"42","author":"Delgado-Escueta","year":"1992","journal-title":"Neurology"},{"key":"S1092852900002327_ref106","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1176\/ajp.153.5.592","article-title":"Phamacologic management of psychiatric illness during pregnancy: dilemmas and guidelines","volume":"153","author":"Altshuler","year":"1996","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(92)90044-7"},{"key":"S1092852900002327_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2004.01.001"},{"key":"S1092852900002327_ref036","first-page":"34","article-title":"Bipolar rapid cycling: focus on depression as its hallmark","volume":"62","author":"Calabrese","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"S1092852900002327_ref051","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.3.420"},{"key":"S1092852900002327_ref083","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)90346-5"},{"key":"S1092852900002327_ref042","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-5618.2001.30503.x"},{"key":"S1092852900002327_ref108","doi-asserted-by":"publisher","DOI":"10.1136\/adc.45.239.139"},{"key":"S1092852900002327_ref025","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v63n0206"},{"key":"S1092852900002327_ref104","first-page":"234","article-title":"Lamotrigine clearance markedly increases during pregnancy [abstract]","volume":"43","author":"Pennel","year":"2002","journal-title":"Epilepsia"},{"key":"S1092852900002327_ref068","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1991.tb03140.x"},{"key":"S1092852900002327_ref103","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.2.251"},{"key":"S1092852900002327_ref069","first-page":"422","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2000"},{"key":"S1092852900002327_ref126","doi-asserted-by":"publisher","DOI":"10.1097\/00007691-198409000-00003"},{"key":"S1092852900002327_ref072","first-page":"508","article-title":"Postpartum mental illness: a controlled study","volume":"77","author":"Foundeur","year":"1957","journal-title":"Arch Neurol Psychiatry"},{"key":"S1092852900002327_ref081","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5859.135"},{"key":"S1092852900002327_ref046","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(01)00432-3"},{"key":"S1092852900002327_ref059","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(01)01239-2"},{"key":"S1092852900002327_ref011","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v64n1102"},{"key":"S1092852900002327_ref050","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1176\/ajp.149.4.554","article-title":"Comorbidity in mania at first hospitalization","volume":"149","author":"Strakowski","year":"1992","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref038","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(02)00244-0"},{"key":"S1092852900002327_ref080","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)91918-7"},{"key":"S1092852900002327_ref107","first-page":"23","article-title":"Is psychiatry in a crisis because of the complications of the psychopharmaceuticals","volume":"29","author":"Ayd","year":"1968","journal-title":"Dis Nerv Syst."},{"key":"S1092852900002327_ref085","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1176\/ajp.153.5.592","article-title":"Pharmacologic management of psychiatric illness during pregnancy: dilemmas and guidelines","volume":"153","author":"Altshuler","year":"1996","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref133","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.2.226"},{"key":"S1092852900002327_ref136","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199311043291904"},{"key":"S1092852900002327_ref070","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0193-953X(18)30453-2","volume":"12","author":"Hamilton","year":"1989","journal-title":"Postpartum psychiatric syndromes. Psychiatr Clin North Am."},{"key":"S1092852900002327_ref060","doi-asserted-by":"publisher","DOI":"10.3109\/10673229609030544"},{"key":"S1092852900002327_ref027","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(00)00909-4"},{"key":"S1092852900002327_ref034","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.56.7.617"},{"key":"S1092852900002327_ref125","first-page":"39","article-title":"Lamotrigine levels in plasma and breast milk in nursing women and their infants [Abstract]","volume":"21","author":"Ohman","year":"1998","journal-title":"Epikpsia"},{"key":"S1092852900002327_ref044","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.58.5.510"},{"key":"S1092852900002327_ref028","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(98)00003-2"},{"key":"S1092852900002327_ref033","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(95)00295-2"},{"key":"S1092852900002327_ref121","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.158.3.393"},{"key":"S1092852900002327_ref129","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199509283331307"},{"key":"S1092852900002327_ref111","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.8.1342"},{"key":"S1092852900002327_ref023","first-page":"5","article-title":"Issues in the treatment of women with bipolar illness","volume":"58","author":"Leibenluft","year":"1997","journal-title":"J Clin Psychiatry"},{"key":"S1092852900002327_ref030","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v61n0514"},{"key":"S1092852900002327_ref132","doi-asserted-by":"publisher","DOI":"10.1159\/000067719"},{"key":"S1092852900002327_ref055","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1983.01790040068010"},{"key":"S1092852900002327_ref017","doi-asserted-by":"publisher","DOI":"10.1053\/comp.2001.27901"},{"key":"S1092852900002327_ref004","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1988.01800350011002"},{"key":"S1092852900002327_ref054","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1990.01810170027005"},{"key":"S1092852900002327_ref089","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80610-1"},{"key":"S1092852900002327_ref141","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(02)00341-X"},{"key":"S1092852900002327_ref032","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(98)00076-7"},{"key":"S1092852900002327_ref093","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.2.179"},{"key":"S1092852900002327_ref062","doi-asserted-by":"publisher","DOI":"10.1016\/0010-440X(76)90036-5"},{"key":"S1092852900002327_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00325-7"},{"key":"S1092852900002327_ref118","first-page":"339","article-title":"The course and management of bipolar disorder during pregnancy","volume":"34","author":"Viguera","year":"1998","journal-title":"Psychopharmacol Bull."},{"key":"S1092852900002327_ref040","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2004.01.001"},{"key":"S1092852900002327_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(93)90026-G"},{"key":"S1092852900002327_ref114","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91951-9"},{"key":"S1092852900002327_ref053","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v64n0412"},{"key":"S1092852900002327_ref066","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1176\/ajp.145.2.179","article-title":"Rapid cycling affective disorder: contributing factors and treatment responses in 51 patients","volume":"145","author":"Wehr","year":"1988","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(98)00056-1"},{"key":"S1092852900002327_ref007","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(98)00142-6"},{"key":"S1092852900002327_ref140","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)00806-3"},{"key":"S1092852900002327_ref082","first-page":"551","article-title":"Ebstein's anomaly and maternal lithium exposure during pregnancy","volume":"41","author":"Edmonds","year":"1990","journal-title":"Tetratology"},{"key":"S1092852900002327_ref105","first-page":"224","article-title":"Safety evaluation of haloperidol in the treatment of hyperemesis gravidarum","volume":"9","author":"Van Waes","year":"1969","journal-title":"J Clin Pharmacol."},{"key":"S1092852900002327_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/S0193-953X(03)00036-4"},{"key":"S1092852900002327_ref131","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.12.2606"},{"key":"S1092852900002327_ref021","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.11.1873"},{"key":"S1092852900002327_ref065","first-page":"415","article-title":"Premenstrual tension syndrome in rapid-cycling bipolar affective disorder","volume":"47","author":"Price","year":"1986","journal-title":"J Clin Psychiatry"},{"key":"S1092852900002327_ref020","volume-title":"Structured Clinical Interview for the DSM-IV-TR Axis I Disorders, Research Version, Patient Edition (SCID1\/P)","author":"First","year":"2001"},{"key":"S1092852900002327_ref086","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1176\/ajp.135.7.801","article-title":"Side effects in the neonate from psychotropic agents excreted through breast-feeding","volume":"135","author":"Ananth","year":"1978","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref048","doi-asserted-by":"publisher","DOI":"10.1089\/104454603322163899"},{"key":"S1092852900002327_ref139","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410390506"},{"key":"S1092852900002327_ref109","first-page":"142","article-title":"A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania","volume":"57","author":"McElroy","year":"1996","journal-title":"J Clin Psychiatry"},{"key":"S1092852900002327_ref041","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-440X(98)90080-3"},{"key":"S1092852900002327_ref037","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-5618.1999.10109.x"},{"key":"S1092852900002327_ref122","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1176\/ajp.152.11.1641","article-title":"Postpartum prophylaxis for women with bipolar disorder","volume":"152","author":"Cohen","year":"1995","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref123","first-page":"167","article-title":"Serum levels of valproate and carbamazepine in breastfeeding mother-infant pairs","volume":"18","author":"Wisner","year":"1998","journal-title":"Psychophamacology (Berl)"},{"key":"S1092852900002327_ref057","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v63n0306"},{"key":"S1092852900002327_ref012","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291797005928"},{"key":"S1092852900002327_ref135","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v61n0305"},{"key":"S1092852900002327_ref095","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1980.tb04320.x"},{"key":"S1092852900002327_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(00)00203-2"},{"key":"S1092852900002327_ref018","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00327-0"},{"key":"S1092852900002327_ref052","first-page":"239","article-title":"Nurnberger JI. Women with bipolar disorder: findings from the NIMH Genetics Initiative Sample","volume":"34","author":"Blehar","year":"1998","journal-title":"Psychopharmacol Bull."},{"key":"S1092852900002327_ref005","doi-asserted-by":"publisher","DOI":"10.1126\/science.7638596"},{"key":"S1092852900002327_ref043","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00003-4"},{"key":"S1092852900002327_ref113","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7162.839"},{"key":"S1092852900002327_ref039","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v64n1213"},{"key":"S1092852900002327_ref035","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1176\/ajp.149.12.1633","article-title":"Clinical and research implications of the diagnosis of dysphoric or mixed mania or hypomania","volume":"149","author":"McElroy","year":"1992","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref071","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1981.01780320109013"},{"key":"S1092852900002327_ref015","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(98)00158-X"},{"key":"S1092852900002327_ref076","first-page":"51","article-title":"Evaluation of late onset bipolar illness during menopause","volume":"59","author":"Ishimaru-Tseng","year":"2000","journal-title":"Hawaii Med J."},{"key":"S1092852900002327_ref115","doi-asserted-by":"publisher","DOI":"10.1159\/000056242"},{"key":"S1092852900002327_ref128","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000125745.60149.c6"},{"key":"S1092852900002327_ref130","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.52.1.401"},{"key":"S1092852900002327_ref031","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1994.tb01495.x"},{"key":"S1092852900002327_ref019","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.52.1.51"},{"key":"S1092852900002327_ref137","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1995.tb01045.x"},{"key":"S1092852900002327_ref090","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(73)90876-4"},{"key":"S1092852900002327_ref024","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852900012335"},{"key":"S1092852900002327_ref064","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-5618.2003.00010.x"},{"key":"S1092852900002327_ref077","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(85)90039-4"},{"key":"S1092852900002327_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00332-4"},{"key":"S1092852900002327_ref091","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5859.137"},{"key":"S1092852900002327_ref138","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410430406"},{"key":"S1092852900002327_ref117","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1994.03510260078033"},{"key":"S1092852900002327_ref063","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-7138(09)60206-5"},{"key":"S1092852900002327_ref100","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.4.944"},{"key":"S1092852900002327_ref127","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)90216-4"},{"key":"S1092852900002327_ref101","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198207060-00003"},{"key":"S1092852900002327_ref112","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1055\/s-2000-7974","article-title":"Healthy outcome under olanzapine treatment in a pregnant woman","volume":"33","author":"Kirchheiner","year":"2000","journal-title":"Pharmacopsychiatry"},{"key":"S1092852900002327_ref058","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.1.112"},{"key":"S1092852900002327_ref119","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.12.1933"},{"key":"S1092852900002327_ref067","first-page":"70","volume-title":"Psychiaric Aspects of Pregnancy in Women's Mental Health. A Comprehensive Textbook","author":"Nonacs","year":"2002"},{"key":"S1092852900002327_ref074","first-page":"3","volume-title":"Postpartum Mood Disorders","author":"Attia","year":"1999"},{"key":"S1092852900002327_ref075","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v63n0403"},{"key":"S1092852900002327_ref045","volume-title":"Manic Depressive Illness","author":"Goodwin","year":"1990"},{"key":"S1092852900002327_ref079","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.4.608"},{"key":"S1092852900002327_ref110","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-200008000-00002"},{"key":"S1092852900002327_ref120","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1071520"},{"key":"S1092852900002327_ref010","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199504000-00012"},{"key":"S1092852900002327_ref029","first-page":"S5","article-title":"The longitudinal course of recurrent affective illness: life chart data from research patients at the NIMH","volume":"317","author":"Roy-Byrne","year":"1985","journal-title":"Acta Psych Scand."},{"key":"S1092852900002327_ref124","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1542\/peds.100.6.1035","article-title":"Breastfeeding and the use of human milk","volume":"100","author":"Gartner","year":"1997","journal-title":"Pediatrics"},{"key":"S1092852900002327_ref056","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v61n0306"},{"key":"S1092852900002327_ref092","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-011-7197-7_48"},{"key":"S1092852900002327_ref078","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1176\/ajp.147.7.907","article-title":"Effect of menstrual cycle phase and oral contraceptive use on serum lithium levels after a loading dose of lithium in normal women","volume":"147","author":"Chamberlain","year":"1990","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref116","first-page":"663","article-title":"Multi-institutional atudy on reratogenicity and fetal toxicity of antiepileptic drugs: a report of a collaborative study group in Japan","volume":"21","author":"Nakane","year":"1980","journal-title":"Epikpsia"},{"key":"S1092852900002327_ref097","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1994.tb05952.x"},{"key":"S1092852900002327_ref022","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1176\/ajp.153.2.163","article-title":"Women with bipolar illness: clinical and research issues","volume":"153","author":"Leibenluft","year":"1996","journal-title":"Am J Psychiatry"},{"key":"S1092852900002327_ref099","doi-asserted-by":"publisher","DOI":"10.1006\/ebeh.2001.0283"},{"key":"S1092852900002327_ref047","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00321-X"},{"key":"S1092852900002327_ref049","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.5.883"},{"key":"S1092852900002327_ref096","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198906223202505"},{"key":"S1092852900002327_ref094","doi-asserted-by":"publisher","DOI":"10.1053\/seiz.1999.0295"},{"key":"S1092852900002327_ref026","doi-asserted-by":"publisher","DOI":"10.1007\/BF00344125"}],"container-title":["CNS Spectrums"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1092852900002327","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T16:38:24Z","timestamp":1557160704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1092852900002327\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":141,"journal-issue":{"issue":"S7","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["S1092852900002327"],"URL":"https:\/\/doi.org\/10.1017\/s1092852900002327","relation":{},"ISSN":["1092-8529","2165-6509"],"issn-type":[{"value":"1092-8529","type":"print"},{"value":"2165-6509","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,8]]}}}