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Increasingly, Parkinson's disease has been associated with a broad spectrum of non-motor symptoms, such as olfactory loss, sleep disorders, autonomic dysfunction, cognitive impairment, psychosis, depression, anxiety, and apathy. In addition, a minority of Parkinson's disease patients develop compulsive behaviors while receiving dopamine-replacement therapy, including medication hoarding, pathological gambling, binge eating, hyperlibidinous behavior, compulsive shopping, and punding. These behaviors may result in psychosocial impairment for patients and therapeutic challenges for clinicians. This article reviews the anatomic substrates, behavioral spectrum, associated factors, and potential treatments for dopamine-replacement therapy-related compulsions in Parkinson's disease.<\/jats:p>","DOI":"10.1017\/s1092852900013778","type":"journal-article","created":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T01:00:34Z","timestamp":1470099634000},"page":"690-698","source":"Crossref","is-referenced-by-count":53,"title":["Impulse-Control Disorders in Parkinson's Disease"],"prefix":"10.1017","volume":"13","author":[{"given":"Joseph M.","family":"Ferrara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Stacy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2014,11,7]]},"reference":[{"key":"S1092852900013778_ref075","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20772"},{"key":"S1092852900013778_ref074","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.102061"},{"key":"S1092852900013778_ref073","first-page":"247","article-title":"Hypersexuality after pallidal surgery in Parkinson disease","volume":"15","author":"Roane","year":"2002","journal-title":"Neuropsychiatry Neuropsychol Behav Neurol"},{"key":"S1092852900013778_ref072","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.16.1.37"},{"key":"S1092852900013778_ref071","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10265"},{"key":"S1092852900013778_ref070","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.72.6.701"},{"key":"S1092852900013778_ref069","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2006.07.011"},{"key":"S1092852900013778_ref068","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20501"},{"key":"S1092852900013778_ref067","doi-asserted-by":"publisher","DOI":"10.1097\/01.mjt.0000151861.59698.26"},{"key":"S1092852900013778_ref066","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-200105000-00009"},{"key":"S1092852900013778_ref065","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21770"},{"key":"S1092852900013778_ref063","first-page":"23","article-title":"Prevalence and factors associated with dopaminergic-medication induced impulse control behaviors in restless legs syndrome","author":"Voon","year":"2008","journal-title":"Mov Disord"},{"key":"S1092852900013778_ref060","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20757"},{"key":"S1092852900013778_ref059","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.64.2.212"},{"key":"S1092852900013778_ref058","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.63.2.298-a"},{"key":"S1092852900013778_ref057","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21072"},{"key":"S1092852900013778_ref056","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(03)00529-5"},{"key":"S1092852900013778_ref053","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2006.04.017"},{"key":"S1092852900013778_ref052","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-004-0238-z"},{"key":"S1092852900013778_ref051","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.9.noc50009"},{"key":"S1092852900013778_ref048","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21303"},{"key":"S1092852900013778_ref047","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000252368.25106.b6"},{"key":"S1092852900013778_ref046","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.029041"},{"key":"S1092852900013778_ref045","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000094200.44303.F3"},{"key":"S1092852900013778_ref044","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20288"},{"key":"S1092852900013778_ref043","unstructured":"Weintraub D , Koester J , Potenza MN , et al. 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