{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T07:21:35Z","timestamp":1770016895779,"version":"3.49.0"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T00:00:00Z","timestamp":1415318400000},"content-version":"unspecified","delay-in-days":2411,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CNS spectr."],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Tics and Tourette syndrome are common comorbidities of patients diagnosed with attention-deficit\/hyperactivity disorder (ADHD). One of the mainstay pharmacologic therapies for ADHD has been stimulants. However, this class of drugs has been associated with tic exacerbations, thus limiting their utility in this patients subgroup. Atomoxetine has been explored as an alternative treatment as one of the few non-stimulants available to treat ADHD. Early data identifies atomoxetine's influence on Tourette symptomatology to be not merely equivocal but potentially suppressive in the manifestation of tics. There are, however, case studies describing patients experiencing recurrences of tics following treatment with atomoxetine. We present a unique case of a patient, without any prior history of a movement disorder, who developed tics following a single dose of atomoxetine that did not improve until interventional therapy was initiated.<\/jats:p>","DOI":"10.1017\/s1092852900016412","type":"journal-article","created":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T05:00:05Z","timestamp":1470114005000},"page":"301-303","source":"Crossref","is-referenced-by-count":16,"title":["Development of Tics in a Thirteen-Year-Old Male Following Atomoxetine Use"],"prefix":"10.1017","volume":"13","author":[{"given":"Jessica","family":"Sears","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin C.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,11,7]]},"reference":[{"key":"S1092852900016412_ref004","doi-asserted-by":"publisher","DOI":"10.1097\/01.chi.0000132833.12842.4e"},{"key":"S1092852900016412_ref003","first-page":"50","article-title":"Safety profile of atomoxetine in the treatment of children and adolescents with ADHD","volume":"63","author":"Wernicke","year":"2002","journal-title":"J Clin Psychiatry"},{"key":"S1092852900016412_ref002","first-page":"305","volume-title":"Current Management in Child Neurology","author":"Mink","year":"2002"},{"key":"S1092852900016412_ref001","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-004-1010-x"},{"key":"S1092852900016412_ref005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1977.tb00425.x"},{"key":"S1092852900016412_ref012","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2005.15.331"},{"key":"S1092852900016412_ref011","unstructured":"McCracken JT , Sallee FR , Leonard HL , et al. Improvement of ADHD by atomoxetine in children with tic disorders. Study presented at: Annual Meeting of the American Academy of Child and Adolescent Psychiatry: Miami, Fla; 2003."},{"key":"S1092852900016412_ref007","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S1056-4993(18)30455-3","article-title":"Attention deficit\/hyperactivity disorder: the stimulants","volume":"4","author":"Greenhill","year":"1995","journal-title":"Child Adolesc Psychiatr Clin North Am"},{"key":"S1092852900016412_ref006","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1542\/peds.86.2.184","article-title":"Side effects of methylphenidate in children with attention deficit hyperactivity disorder: a systemic, placebo-controlled evaluation","volume":"86","author":"Barkley","year":"1990","journal-title":"Pediatrics"},{"key":"S1092852900016412_ref009","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S1056-4993(18)30108-1","article-title":"The stimulants revisited","volume":"9","author":"Wilens","year":"2000","journal-title":"Child Adolesc Psychiatr Clin N Am"},{"key":"S1092852900016412_ref013","doi-asserted-by":"publisher","DOI":"10.1080\/00207411.1975.11448680"},{"key":"S1092852900016412_ref010","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-199508000-00006"},{"key":"S1092852900016412_ref008","doi-asserted-by":"publisher","DOI":"10.1177\/001440299306000209"}],"container-title":["CNS Spectrums"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1092852900016412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T17:55:09Z","timestamp":1656957309000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1092852900016412\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S1092852900016412"],"URL":"https:\/\/doi.org\/10.1017\/s1092852900016412","relation":{},"ISSN":["1092-8529","2165-6509"],"issn-type":[{"value":"1092-8529","type":"print"},{"value":"2165-6509","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}