{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T18:10:08Z","timestamp":1656958208739},"reference-count":71,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T00:00:00Z","timestamp":1415318400000},"content-version":"unspecified","delay-in-days":4754,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CNS spectr."],"published-print":{"date-parts":[[2001,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Rasmussen's syndrome (chronic encephalitis with epilepsy) is a rare neurological disorder of unknown cause characterized by severe epilepsy, hemiplegia, dementia, and inflammation of the brain, and progressive functional and structural destruction of a single cerebral hemisphere. While one mechanism underlying the pathogenesis of Rasmussens encephalitis has been hypothesized to be mediated by production of excitotoxic GluR3 autoantibodies to the a-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor, other neuropathological etiologies have also been indicated. Proposed therapies have included antiepileptics, steroids, antiviral agents, alpha-interferon, and immunoglobulin. The mainstay of therapy is surgical hemispherectomy. To date, no medical therapies have permanently halted neurologic deterioration.<\/jats:p>","DOI":"10.1017\/s1092852900021775","type":"journal-article","created":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T03:16:45Z","timestamp":1470107805000},"page":"398,409-416","source":"Crossref","is-referenced-by-count":2,"title":["Rasmussen's Syndrome: Intractable Epilepsy and Progressive Neurological Deterioration From a Unilateral Central Nervous System Disease"],"prefix":"10.1017","volume":"6","author":[{"given":"Paul R.","family":"Carney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,11,7]]},"reference":[{"key":"S1092852900021775_ref036","first-page":"37","volume-title":"Chronic Encephalitis and Epilepsy, Rasmussen's Syndrome","author":"So","year":"1991"},{"key":"S1092852900021775_ref039","first-page":"47","volume-title":"Chronic Encephalitis and Epilepsy: Rasmussen's 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