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In order to clarify the role of attention and inhibitory control in pediatric OCD and TD, a continuous performance test (CPT) was administered to a cohort of children and adolescents with OCD alone, TD alone, and OCD+TD.<\/jats:p><\/jats:sec><jats:sec id=\"S1092852914000467_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A clinical cohort of 48 children and adolescents with OCD alone (n<jats:bold>=<\/jats:bold>20), TD alone (n<jats:bold>=<\/jats:bold>15), or OCD+TD (n<jats:bold>=<\/jats:bold>13) was interviewed clinically and administered the Conners Continuous Performance Test II (CPT-II). The Conners CPT-II is a 14-minute normed computerized test consisting of 6 blocks. It taps into attention, inhibitory control, and sustained attention cognitive domains. Key parameters include errors of omission (distractability), commission (inhibitory control), and variable responding over time (sustained attention).<jats:italic>Diagnostic and Statistical Manual of Mental Disorders<\/jats:italic>, 4th Edition (DSM-IV) criteria were applied in a best-estimate process to diagnose OCD, TD, ADHD, and anxiety disorders.<\/jats:p><\/jats:sec><jats:sec id=\"S1092852914000467_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Children with OCD+TD had more errors of omission (<jats:italic>p<\/jats:italic><jats:bold>=<\/jats:bold>0.03), and more hit RT block change (<jats:italic>p<\/jats:italic><jats:bold>=<\/jats:bold>0.003) and hit SE block change (<jats:italic>p<\/jats:italic><jats:bold>=<\/jats:bold>0.02) than subjects with OCD alone and TD alone. These deficits in sustained attention were associated with younger age and hoarding tendencies. A clinical diagnosis of ADHD in the OCD+TD group also determined worse sustained attention.<\/jats:p><\/jats:sec><jats:sec id=\"S1092852914000467_abs4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>A deficit in sustained attention, a core marker of ADHD, is also a marker of OCD+TD, compared to OCD alone and TD alone. Biological correlates of sustained attention may serve to uncover the pathophysiology of OCD and TD through genetic and imaging studies.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1092852914000467","type":"journal-article","created":{"date-parts":[[2014,10,9]],"date-time":"2014-10-09T07:24:19Z","timestamp":1412839459000},"page":"479-489","source":"Crossref","is-referenced-by-count":17,"title":["Continuous performance test in pediatric obsessive-compulsive disorder and tic disorders: the role of sustained attention"],"prefix":"10.1017","volume":"20","author":[{"given":"Ilse M.","family":"Lucke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatmata","family":"Conteh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Federline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huyngmo","family":"Sung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Specht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A.","family":"Grados","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,10,9]]},"reference":[{"key":"S1092852914000467_ref65","doi-asserted-by":"publisher","DOI":"10.1023\/A:1025405216339"},{"key":"S1092852914000467_ref61","doi-asserted-by":"publisher","DOI":"10.1037\/a0014552"},{"key":"S1092852914000467_ref56","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20044"},{"key":"S1092852914000467_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2010.10.004"},{"key":"S1092852914000467_ref63","doi-asserted-by":"publisher","DOI":"10.1177\/0145445513504431"},{"key":"S1092852914000467_ref54","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2242"},{"key":"S1092852914000467_ref60","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617710000895"},{"key":"S1092852914000467_ref49","doi-asserted-by":"publisher","DOI":"10.1037\/1528-3542.7.2.336"},{"key":"S1092852914000467_ref48","doi-asserted-by":"publisher","DOI":"10.1037\/0096-3445.133.3.339"},{"key":"S1092852914000467_ref30","doi-asserted-by":"publisher","DOI":"10.1186\/1744-9081-4-29"},{"key":"S1092852914000467_ref44","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8760(95)00045-3"},{"key":"S1092852914000467_ref41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5215.2011.00562.x"},{"key":"S1092852914000467_ref7","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/417516"},{"key":"S1092852914000467_ref62","first-page":"1155","article-title":"Neuropsychological functioning in children with Tourette syndrome with and without attention-deficit\/hyperactivity disorder","volume":"49","author":"Sukhodolsky","year":"2010","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"S1092852914000467_ref38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.2007.01609.x"},{"key":"S1092852914000467_ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820210068008"},{"key":"S1092852914000467_ref35","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v61n0708"},{"key":"S1092852914000467_ref57","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.1.142"},{"key":"S1092852914000467_ref33","doi-asserted-by":"publisher","DOI":"10.1177\/070674379904401010"},{"key":"S1092852914000467_ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-012-0278-5"},{"key":"S1092852914000467_ref28","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199804000-00001"},{"key":"S1092852914000467_ref27","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199211000-00010"},{"key":"S1092852914000467_ref25","unstructured":"Conners CK . 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