{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T05:49:17Z","timestamp":1780984157041,"version":"3.54.1"},"reference-count":35,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T00:00:00Z","timestamp":1553644800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CNS Spectr."],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec id=\"S1092852918001554_as1\"><jats:title>Objective<\/jats:title><jats:p>We assessed self-reported drives for alcohol use and their impact on clinical features of alcohol use disorder (AUD) patients. Our prediction was that, in contrast to \u201caffectively\u201d (reward or fear) driven drinking, \u201chabitual\u201d drinking would be associated with worse clinical features in relation to alcohol use and higher occurrence of associated psychiatric symptoms.<\/jats:p><\/jats:sec><jats:sec id=\"S1092852918001554_as2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Fifty-eight <jats:italic>Diagnostic and Statistical Manual of Mental Disorders<\/jats:italic>, Fourth Edition (DSM-IV) alcohol abuse patients were assessed with a comprehensive battery of reward- and fear-based behavioral tendencies. An 18-item self-report instrument (the Habit, Reward and Fear Scale; HRFS) was employed to quantify affective (fear or reward) and non-affective (habitual) motivations for alcohol use. To characterize clinical and demographic measures associated with habit, reward, and fear, we conducted a partial least squares analysis.<\/jats:p><\/jats:sec><jats:sec id=\"S1092852918001554_as3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Habitual alcohol use was significantly associated with the severity of alcohol dependence reflected across a range of domains and with lower number of detoxifications across multiple settings. In contrast, reward-driven alcohol use was associated with a single domain of alcohol dependence, reward-related behavioral tendencies, and lower number of detoxifications.<\/jats:p><\/jats:sec><jats:sec id=\"S1092852918001554_as4\"><jats:title>Conclusion<\/jats:title><jats:p>These results seem to be consistent with a shift from goal-directed to habit-driven alcohol use with severity and progression of addiction, complementing preclinical work and informing biological models of addiction. Both reward-related and habit-driven alcohol use were associated with lower number of detoxifications, perhaps stemming from more benign course for the reward-related and lack of treatment engagement for the habit-related alcohol abuse group. Future work should further explore the role of habit in this and other addictive disorders, and in obsessive-compulsive related disorders.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1092852918001554","type":"journal-article","created":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T16:58:57Z","timestamp":1553705937000},"page":"597-604","source":"Crossref","is-referenced-by-count":21,"title":["A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder"],"prefix":"10.1017","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6981-8658","authenticated-orcid":false,"given":"Marcelo","family":"Piquet-Pess\u00f4a","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7014-8121","authenticated-orcid":false,"given":"Samuel R.","family":"Chamberlain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rico S. 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