{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:05:51Z","timestamp":1793822751460,"version":"4.6.1"},"reference-count":49,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CNS Spectr."],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S109285292000111X_sec2\"><jats:title>Background<\/jats:title><jats:p>Relatively few studies have assessed the prevalence, correlates, and independent impact on quality of life (QoL) of trichotillomania (TTM) in large samples.<\/jats:p><\/jats:sec><jats:sec id=\"S109285292000111X_sec3\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Consecutive participants (N = 7639) were recruited from a cross-sectional web-based study. Sociodemographic data were collected and several validated self-reported mental health measures were completed (Minnesota Impulsive Disorders Interview, Hypomania checklist, Fagerstr\u00f6m Test for Nicotine Dependence, Alcohol Use Disorders Identification Test, Early Trauma Inventory Self Report\u2013Short Form, and the Symptom Checklist-90\u2013Revised Inventory)<jats:italic>.<\/jats:italic> Health-related QoL was assessed with the World Health Organization QoL abbreviated scale (WHOQOL-Bref). Multivariable models adjusted associations to potential confounders.<\/jats:p><\/jats:sec><jats:sec id=\"S109285292000111X_sec4\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>The sample was predominantly composed of young females (71.3%; mean age: 27.2 \u00b1 7.9 years). The prevalence of probable TTM was 1.4% (95% confidence intervals [CI]: 1.2-1.7), and was more common among females. Participants with probable TTM had a greater likelihood of having co-occurring probable depression (adjusted odds ratio [ORadj] = 1.744; 95% CI: 1.187-2.560), tobacco (ORadj = 2.250; 95% CI: 1.191-4.250), and alcohol (ORadj = 1.751; 95% CI: 1.169-2.621) use disorders. Probable TTM was also independently associated with suicidal ideation (ORadj = 1.917; 95% CI: 1.224-3.003) and exposure to childhood sexual abuse (ORadj = 1.221; 95% CI: 1.098-1.358). In addition, a positive screen for TTM had more impaired physical and mental QoL.<\/jats:p><\/jats:sec><jats:sec id=\"S109285292000111X_sec5\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>TTM was associated with a positive screen for several psychiatric comorbidities as well as impaired physical and psychological QoL. Efforts towards the recognition and treatment of TTM across psycho-dermatology services are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s109285292000111x","type":"journal-article","created":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T05:09:25Z","timestamp":1586322565000},"page":"282-289","source":"Crossref","is-referenced-by-count":13,"title":["Trichotillomania\u2014psychopathological correlates and associations with health-related quality of life in a large sample"],"prefix":"10.1017","volume":"26","author":[{"given":"Andre P.","family":"Bezerra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myrela O.","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2012-871X","authenticated-orcid":false,"given":"Michel","family":"Maes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4021-5829","authenticated-orcid":false,"given":"Donatella","family":"Marazziti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo R.","family":"Nunes-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Solmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Firth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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