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Making the case of obsessive\u2013compulsive disorder (OCD), a lot have been made in this direction. Indeed, while the Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnosis of OCD aimed to delineate a homogeneous group of patients, it is now clear that OCD is instead an heterogeneous disorders both in terms of neural networks, immunological, genetic, and clinical profiles. In this view, a convergent amount of literature, in the last years, indicated that OCD patients with an early age at onset seem to have a specific clinical and biological profile, suggesting it as a neurodevelopmental disorder. Also, these patients tend to have a worse outcome respect to adult-onset patients and there is growing evidence that early-interventions could potentially improve their prognosis. Therefore, the aim of the present paper is to review the current available genetic, immunological, neurobiological, cognitive, and clinical data in favor of a more biologically precise subtype of OCD: the early-onset subtype. We also briefly resume current available recommendations for the clinical management of this specific population.<\/jats:p>","DOI":"10.1017\/s1092852921000122","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T08:01:50Z","timestamp":1612166510000},"page":"1-7","source":"Crossref","is-referenced-by-count":18,"title":["Early onset obsessive\u2013compulsive disorder: the biological and clinical 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